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The antitumor effects of interferon

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Interferons show antitumor activity in patients with various malignancies. The mechanism(s) of the antitumor effects are not altogether clear. In one experimental animal model discussed herein, mice were injected with Friend erythroleukemia cells and treated with mouse interferon α/β. The results suggest that interferon does not act directly on the tumor cells but acts via host mechanisms that are still ill defined.

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Correspondence to Ion Gresser.

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This article is dedicated to the memory of Professor John F. Enders.

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Gresser, I. The antitumor effects of interferon. Med. Oncol. & Tumor Pharmacother. 3, 223 (1986). https://doi.org/10.1007/BF02934998

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Key words

  • Interferon
  • Antitumor
  • Patients
  • Mice