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Treatment of metastatic sweat gland carcinoma by a four drug combination chemotherapy: Response in two cases

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Two patients with metastatic sweat gland carcinoma were treated with a combination chemotherapy consisting of adriamycin, cyclophosphamide, vincristine and bleomycin. In one patient, a complete remission of two years’ duration, and in the other a partial remission (4 + months) were achieved. A review of the literature about chemotherapy in metastatic sweat gland carcinoma is given.

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  1. 1.

    Mehregan A H, Hashimoto K, Rahbari H: Eccrine adenocarcinoma.Arch Derm 119, 104–114 (1983).

  2. 2.

    Lever W F, Schaumburg-Lever G:Histopathology of the Skin, 6th edn, pp. 575–589. Philadelphia, G. B. Lippincott (1983).

  3. 3.

    Hirsh L F, Enterline H T, Rosato E F, Rosato F E: Sweat gland carcinoma.Ann Surg 174, 283–286 (1971).

  4. 4.

    Chow C W, Campbell P E, Burry A F: Sweat gland carcinomas in children.Cancer 53, 1222–1227 (1984).

  5. 5.

    El-Domeiri A A, Brasfield R D, Huvos A G, Strong E W: Sweat gland carcinoma: a clinico-pathologic study of 83 patients.Ann Surg 173, 270–274 (1971).

  6. 6.

    Warkel R L, Helwig E B: Apocrine gland adenoma and adenocarcinoma of the axilla.Arch Derm 114, 198–203 (1978).

  7. 7.

    Shaw M, McKee P H, Lowe D, Black M M: Malignant eccrine poroma: a study of twenty-seven cases.Br J Derm 107, 675–680 (1982).

  8. 8.

    Teloh H A, Balkin R B, Grier J P: Metastasizing sweat-gland carcinoma.Arch Derm 76, 80–86 (1957).

  9. 9.

    Dave V K: Eccrine sweat gland carcinoma with metastases.Br J Derm 86, 95–97 (1972).

  10. 10.

    Grosshans E, Vetter J M, Capesius C: Poromes eccrines malins.Ann Anat Path 20, 381–394 (1975).

  11. 11.

    Krinitz K: Malignes intraepidermales ekkrines Porom.Z. Haut-Geschl-Kr 47, 9–17 (1972).

  12. 12.

    Yeung K-Y, Stinson J C: Mucinous (adenocystic) carcinoma of sweat glands with widespread metastasis.Cancer 39, 2556–2562 (1977).

  13. 13.

    Bassermann R, Ludwig G, Hölzel D, Eder M: Hämatogene Orgammetastasen — welcher Primärtumor?Pathologe 5, 13–20 (1984).

  14. 14.

    Nissenblatt M J: Carcinoma with unknown primary tumor (CUP syndrome).South Med J 74, 1497–1502 (1981).

  15. 15.

    Penneys N S, Nadji M, Ziegels-Weissman J, Ketabchi M, Morales A R: Carcinoembryonic antigen in sweat-gland carcinomas.Cancer,50, 1608–1611 (1982).

  16. 16.

    Einhorn L H, Fee W H, Farber M O, Livingston R B, Gottlieb J A: Improved chemotherapy for small-cell undifferentiated lung cancer.J Am Med Assoc 235, 1225–1229 (1976).

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Correspondence to Jörg Mezger.

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Mezger, J., Remberger, K., Schalhorn, A. et al. Treatment of metastatic sweat gland carcinoma by a four drug combination chemotherapy: Response in two cases. Med. Oncol. & Tumor Pharmacother. 3, 29–34 (1986). https://doi.org/10.1007/BF02934573

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  • Vincristine
  • Bleomycin
  • Adriamycin
  • Combination Chemotherapy
  • Basal Cell Carcinoma