Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Clinical effects of enteral and parenteral nutrition preceding cancer surgery

  • 24 Accesses

Abstract

Parenteral and enteral nutrition have become major tools in the nutritional management of cancer patients perioperatively. The purpose of this article is to see if there is evidence from prospective controlled trials that parenteral and enteral nutrition preceding cancer surgery are of clinical benefit. From our investigation and from 8 other controlled, randomized clinical investigations the following conclusions can be drawn: (1) Parenteral and enteral nutrition preceding cancer surgery improve nutritional parameters; (2) Parenteral and enteral nutrition preceding cancer surgery may decrease postoperative morbidity and mortality, but this beneficial effect may not be limited to malnourished patients; (3) If enteral nutrition can provide the same amount of proteins and calories as parenteral nutrition can, parenteral and enteral nutrition are equal with regard to clinical effects.

This is a preview of subscription content, log in to check access.

References

  1. 1.

    Goodgame J T: A critical assessment of the indications for total parenteral nutrition.Surg Gynecol Obstet 151, 433 (1980).

  2. 2.

    Brennan M F: Total parenteral nutrition in the cancer patient.New Engl J Med 305, 375 (1981).

  3. 3.

    Muggia-Sullam M, Fischer J E:Current Concepts of Indications for Preoperative Parenteral Nutrition, vol. 1, pp. 579–598. London, Clinics in Anaesthesiology, W. B. Saunders (1983).

  4. 4.

    Jensen S, Ginnerup P: Complete parenteral nutrition perioperatively for patients with rectal adenocarcinoma. Nitrogen balance and the clinical course.Ugeskr Laeger 144, 460 (1982).

  5. 5.

    Holter A R, Fischer J E: The effects of perioperative hyperalimentation in complications in patients with carcinoma and weight loss.J Surg Res 23, 31 (1977).

  6. 6.

    Moghissi K, Hornshaw J, Teasdale P R, Daves E A: Parenteral nutrition in carcinoma of the oesophagus treated by surgery: nitrogen balance and clinical studies.Br J Surg 64, 125 (1977).

  7. 7.

    Heatley R V, Williams R H P, Lewis M H: Preoperative intravenous feeding—a controlled trial.Postgrad Med J 55, 541 (1979).

  8. 8.

    Collins J P, Oxby C B, Hill G L: Intravenous aminoacids and intravenous hyperalimentation as protein-sparing therapy after major surgery.Lancet i, 788 (1978).

  9. 9.

    Young G A, Hill G L: A controlled study of protein-sparing therapy after excision of the rectum.Ann Surg 192, 183 (1980).

  10. 10.

    Thompson B R, Julian T B, Stremple J F: Perioperative total parenteral nutrition on patients with gastrointestinal cancer.J Surg Res 30, 497 (1981).

  11. 11.

    Müller J M, Brenner M, Dienst C, Pichlmair H: Preoperative parenteral feeding in patients with gastrointestinal carcinoma.Lancet i, 68 (1982).

  12. 12.

    Lim S T K, Choa R G, Lam K H, Wong J, Ong B G: Total parenteral nutrition versus gastrostomy in the preoperative preparation of patients with carcinoma of the oesophagus.Br J Surg 68, 69 (1981).

  13. 13.

    Sako K, Loré J M, Kaufmann S, Mohamed S, Ruzak Bakamfian V, Reese P: Parenteral hyperalimentation in surgical patients with head and neck cancer: a randomized study.J Surg Oncol 16, 391 (1981).

Download references

Author information

Correspondence to Stanley Jensen.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Jensen, S. Clinical effects of enteral and parenteral nutrition preceding cancer surgery. Med. Oncol. & Tumor Pharmacother. 2, 225 (1985). https://doi.org/10.1007/BF02934552

Download citation

Key words

  • Parenteral nutrition
  • Enteral nutrition
  • Clinical effects
  • Perioperatively
  • Cancer surgery