The protective effect of the traditional Chinese compound medicine Yuxingtong (YXT) in capsule form on the experimental acute myocardial ischemia formation has been studied in dogs. The plasma endothelin concentration and serum creatine phosphokinase activity were measured after coronary occlusion in different medication groups and compared with the saline control group. Results showed that YXT could significantly lowered the plasma endothelin concentration and the serum creatine phosphokinase activity, it suggested that both YXT and diltiazem have the similar protective effect on acute myocardial ischemia and necrosis in dogs.
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Lei, Y., Chen, K. Effect of Yuxintong capsule on serum creatine phosphokinase activity and plasma endothelin concentration in acute myocardial ischemic dogs) capsule on serum creatine phosphokinase activity and plasma endothelin concentration in acute myocardial ischemic dogs. CJIM 2, 60–63 (1996). https://doi.org/10.1007/BF02934228
- Yuxintong capsule
- creatine phosphokinase
- acute myocardial ischemia