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Effect of Yuxintong capsule on serum creatine phosphokinase activity and plasma endothelin concentration in acute myocardial ischemic dogs) capsule on serum creatine phosphokinase activity and plasma endothelin concentration in acute myocardial ischemic dogs

Abstract

The protective effect of the traditional Chinese compound medicine Yuxingtong (YXT) in capsule form on the experimental acute myocardial ischemia formation has been studied in dogs. The plasma endothelin concentration and serum creatine phosphokinase activity were measured after coronary occlusion in different medication groups and compared with the saline control group. Results showed that YXT could significantly lowered the plasma endothelin concentration and the serum creatine phosphokinase activity, it suggested that both YXT and diltiazem have the similar protective effect on acute myocardial ischemia and necrosis in dogs.

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References

  1. 2.

    Stewart DJ, Kubac G, Costello K B, et al. Increased plasma endothelin-1 in the early hours of acute myocardial infarction. JACC 1991; 18: 38–43.

  2. 5.

    Kiowski W, Luscher TF, Linder L, et al. Endothelin-1 induced Vasoconstriction in humans reversal by calcium channel blockade but not by nitrovasodilators or endothelium-de-rived relaxing factor. Circulation 1991, 83: 469.

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Correspondence to Yan Lei or Ke-Ji Chen.

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Lei, Y., Chen, K. Effect of Yuxintong capsule on serum creatine phosphokinase activity and plasma endothelin concentration in acute myocardial ischemic dogs) capsule on serum creatine phosphokinase activity and plasma endothelin concentration in acute myocardial ischemic dogs. CJIM 2, 60–63 (1996). https://doi.org/10.1007/BF02934228

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Key Words

  • Yuxintong capsule
  • creatine phosphokinase
  • endothelin
  • acute myocardial ischemia
  • dogs