Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Study on therapeutic mechanism of Xilei powder for peptic ulcer) for peptic ulcer

  • 15 Accesses


One hundred and twenty-eight patients with active peptic ulcer were treated with Xilei powder for 4 weeks, their PGE2 levels in both serum and gastro-duodenal mucosa were significantly higher than those before treatment (P<0.01). The rate of negative conversion of Helicobacter pylori (HP) showed in 63.3% of cases. The distributed density of HP significantly reduced (P<0.01). These results indicated that Xilei powder could heal ulcer probably owing to the increasing of the PGE2 level in gastro-duodenal mucose, and inhibiting the growth and reproduction of HP so that to eliminate the HP, but did not owing to inhibit the gastric acid secretion and the release of gastrin.

This is a preview of subscription content, log in to check access.


  1. 4.

    Robert A, Schultz JR, Nezamis JE, et al. Gastric antisecretory and antiulcer properties of PGE2 15-mehtyl PGE2 and 16, 16-dimethyl PGE2. Gastroenterology 1976; 70(3): 359.

  2. 5.

    Vantrappen C. Effect of 15(R)-15-methy prostaglandin E2 (arbaprostil) on the healing of duodenal ulcer. Gastroenterology 1982; 83(2): 357.

  3. 6.

    Graham DY. Campylobacter pylori and peptic ulcer. Gastroenterology 1989; 96(2): 615.

Download references

Author information

Correspondence to An-Tian Zhang or Lin-Xue Qian or Jing-Ming Guan or Ya-Ju Du or Zeng-Duo Wang or Shao-Hua Li or Hui-Chun Guo.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Zhang, A., Qian, L., Guan, J. et al. Study on therapeutic mechanism of Xilei powder for peptic ulcer) for peptic ulcer. CJIM 2, 39–41 (1996). https://doi.org/10.1007/BF02934219

Download citation

Key Words

  • peptic ulcer
  • Xi-Lei powder
  • prostaglandin E2
  • Helicobacter pylori