Skip to main content
SpringerLink
Log in

Water immersion induced alterations of plasma vasopressin levels and activity of the renin-angiotensin-aldosterone system in noninflammatory acute renal failure and end-stage renal failure

  • Published:
International Urology and Nephrology Aims and scope Submit manuscript

Abstract

Water immersion (WI) induced alterations of plasma renin activity (PRA), plasma aldosterone (Aldo), vasopressin (AVP), sodium and potassium concentrations and plasma volume (PV) were examined in 12 patients with noninflammatory acute renal failure (NARF) in the anuric/oliguric phase, in 20 patients with chronic renal failure (CRF) and in 15 healthy subjects. In all examined groups a significant increase of PV and decrease of PRA, plasma Aldo, AVP after WI were observed. Significantly more marked decreases of PRA were observed in patients with NARF than in those with CRF and in healthy subjects. In patients with NARF the increase of PV was significantly greater than in CRF and in healthy subjects. In patients with NARF a significantly more marked decrease of plasma sodium concentration was also noted after WI than in subjects with CRF and in normals. Only in healthy subjects was a significant negative correlation noted between the WI increase of PV and decrease of plasma AVP level. In healthy subjects, significantly positive correlations were noted between WI induced decrease of PRA and Aldo and between PRA and plasma AVP, respectively. Such correlations were absent in uraemic patients.

In conclusions: (1) patients with CRF and NARF show similar, but quantitatively different responses of PRA, Aldo and AVP secretion to WI as compared with normals; (2) patients with NARF and CRF are characterized by an inappropriate volumetric and osmotic regulation of AVP secretion; (3) in uraemic patients the physiological relationship between the renin-angiotensin system and AVP secretion seems to be dissociated.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Arborelius, M. J., Boldin, U. J., Lija, B., Lundgreen, C. E. G.: Hemodynamic changes in man during immersion with the head above water.Aerosp. Med., 43, 592 (1972).

    PubMed  Google Scholar 

  2. Crane, M., Harris, J. J.: Suppression of plasma aldosterone by partial immersion.Metabolism, 24, 359 (1974).

    Article  Google Scholar 

  3. Diem, K., Leutner, C.: Wissenschaftliche Tabellen Documenta Geigy. G. Thieme, Stuttgart 1975.

    Google Scholar 

  4. Epstein, M.: Cardiovascular and renal effects of head-out water immersion in man. Application of the model in assessment of volumen homeostasis.Circ. Res., 39, 619, (1976).

    PubMed  CAS  Google Scholar 

  5. Epstein, M.: Water immersion and the kidney: implications for volume regulation.Undersca, Biomed. Res., 11, 113 (1984).

    CAS  Google Scholar 

  6. Epstein, M.: Comparison of suppressive effects of water immersion and saline administration on renin-aldosterone system in normal man.J. Clin. Endocrinol. Metab., 48, 358 (1979).

    Google Scholar 

  7. Epstein, M.: Renal, endocrine and hemodynamic effects of water immersion in man.Contr. Nephrol., 41, 174 (1984).

    CAS  Google Scholar 

  8. Greenleaf, J. E., Convertino, V. A., Mangseth, G. R.: Plasma volume during stress: osmolality and red cell volume.J. Appl. Physiol. Respirat. Environ. Exercise Physiol., 47, 1031 (1979).

    CAS  Google Scholar 

  9. Grzeszczak, W.: Influence of blockade of opioid receptors by naloxone on secretion of pituitary, pancreatic, gonadal and adrenal hormones and of PTH in patients with acute and chronic renal failure.Ann. Acad. Med. Siles., II, 1 (1986).

    Google Scholar 

  10. Grzeszczak, W., Kokot, F., Duława, J., Kuska, J.: Influence of naloxone on vasopressin secretion in patients with acute and chronic renal failure.Pol. Arch. Med. Wewn., 74, 176 (1985).

    PubMed  CAS  Google Scholar 

  11. Grzeszczak, W., Kokot, F., Więcek, A.: Effect of water immersion on plasma renin activity, aldosteronemia, vasopressinemia in patients with acute non-inflammatory renal failure.Acta Med. Pol., 27, 101 (1986).

    PubMed  CAS  Google Scholar 

  12. Harrison, N. H., Keil, L. C., Wade, C. A., Silver, J. E., Geelen, G., Greenleaf, J. E.: Effect of hydration on plasma volume and endocrine responses to water immersion.J. Appl. Physiol., 61, 1410 (1986).

    PubMed  CAS  Google Scholar 

  13. Hayward, J. N., Pavasuthipaisit, K., Perez-Lopez, F. R., Sofroniew, M. W.: Radioimmunoassay of arginine vasopressin in Rhesus monkey plasma.Endocrinology, 98, 975 (1976).

    PubMed  CAS  Google Scholar 

  14. Kokot, F.: Laboratory methods used in clinical medicine. National Medical Publisher, Warszawa 1969.

    Google Scholar 

  15. Kokot, F., Jupowiecki, J.: Head out water immersion induced endocrine alterations in hypertensive patients.Przegl. Lek., 42, 316 (1985).

    PubMed  CAS  Google Scholar 

  16. Kokot, F., Kuska, J.: Verhalten der Plasmareninaktivität und des Aldosterons nach Kochsalzbeschränkung und aufrechter Körperlage bei essentieller Hypertonie.Zschr. Inn. Med., 31, 1016 (1976).

    CAS  Google Scholar 

  17. Kokot, F., Kuska, J.: Plasma renin activity in acute renal insufficiency.Nephron, 6, 115 (1969).

    Article  PubMed  CAS  Google Scholar 

  18. Kokot, F., Kuska, J.: Plasma renin activity in patients with acute and chronic renal insufficiency treated by hemodialysisProc. EDTA, 8, 542 (1971).

    Google Scholar 

  19. Kokot, F., Stupnicki, R.: Radioimmunological and radiocompetitive methods used in clinical medicine. National Medical Publisher, Warszawa 1985.

    Google Scholar 

  20. Kokot, F., Więcek, A., Grzeszczak, W., Szczechowska, E., Duława, J.: The water immersion model in nephrology.Contr. Nephrol. (in press).

  21. Korz, R., Fischer, F., Behm, C.: Renin-angiotensin System bei stimulierter Hypervolaemie durch Immersion.Klin. Wochenschr. 23, 1263 (1969).

    Article  Google Scholar 

  22. Lange, I., Lange, S., Echt, P., Gauer, O. H.: Heart volume in relation to body posture and immersion in a thermoneutral bath.Pflügers Arch., 352, 219 (1975).

    Article  Google Scholar 

  23. Osten, B., Kokot, F., Klinkmann, H.: Endokrinologische Störungen bei chronischer Niereninsuffizienz und bei Dauerdialysebehandlung.Dtsch. Gesundh. Wesen, 37, 2113, 2196 (1982).

    Google Scholar 

  24. Paton, A. M., Lever, A. F., Cliver, N. W. J., Medina, A., Briggs, J. D., Morton, J. J., Brown, J. J., Robertson, J. I. S., Fraser, R., Tree, M., Gavras, H.: Plasma angiotensin II, renin substrate and aldosterone concentrations in acute renal failure in man.Clin. Nephrol., 3, 18 (1975).

    PubMed  CAS  Google Scholar 

  25. Shimomoto, K., Watarai, K., Mijahara, M.: A study of plasma vasopressin in patients undergoing chronic hemodialysis.J. Clin. Endocrinol. Metab., 46, 714 (1977).

    Article  Google Scholar 

  26. Vaziri, N. D., Skovsky, R., Warner, A.: Effect of isoosmolar volume reduction during hemofiltration on plasma antidiuretic hormone in patients with chronic renal failure.Int. J. Artif. Organs, 3, 322 (1980).

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Nephrology, Silesian School of Medicine, Katowice, Poland

    F. Kokot, W. Grzeszczak, E. Żukowska-Szczechowska & A. Więcek

Authors
  1. F. Kokot
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. W. Grzeszczak
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. E. Żukowska-Szczechowska
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. A. Więcek
    View author publications

    You can also search for this author in PubMed Google Scholar

About this article

Cite this article

Kokot, F., Grzeszczak, W., Żukowska-Szczechowska, E. et al. Water immersion induced alterations of plasma vasopressin levels and activity of the renin-angiotensin-aldosterone system in noninflammatory acute renal failure and end-stage renal failure. International Urology and Nephrology 22, 285–293 (1990). https://doi.org/10.1007/BF02550408

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02550408

Keywords

Search

Navigation