Advertisement

Pharmaceutisch Weekblad

, Volume 5, Issue 5, pp 252–253 | Cite as

Zinc absorption after oral administration of zinc sulfate

  • J. J. Keyzer
  • E. Oosting
  • B. G. Wolthers
  • F. A. J. Muskiet
Short Communications

Abstract

The administration of 200 mg of ZnSO4.7H2O to six normal healthy males gave rise to increased serum zinc levels when this drug was taken in a fasting state, whereas administration during a light meal caused no increased levels.

Keywords

Public Health Sulfate Zinc Internal Medicine Oral Administration 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Sullivan JF, Jetton MM, Burch RE. A zinc tolerance test. J Lab Clin Med 1979;93:485–92.PubMedGoogle Scholar
  2. 2.
    Solomons NW. Biological availability of zinc in humans. Am J Clin Nutr 1982;35:1048–75.PubMedGoogle Scholar
  3. 3.
    Aamodt RL, Rumble WF, Babcock AK, Foster DM, Henkin RI. Effects of oral zinc loading on zinc metabolism in humans-I: experimental studies. Metabolism 1982;31:326–34.CrossRefPubMedGoogle Scholar
  4. 4.
    Antonson DL, Barak AJ, Vanderhoff JA. Determination of the site of zinc absorption in rat small intestine. J Nutr 1979;109:142–7.PubMedGoogle Scholar
  5. 5.
    Wolman SL, Anderson GH, Marliss EB, Jeejeebhoy KN. Zinc in total parenteral nutrition-requirements and metabolic effects. Gastroenterology 1981;76:458–67.Google Scholar
  6. 6.
    Evans GW, Grace CI, Hahn C. Homeostatic regulation of zinc absorption in the rat. Proc Soc Exp Biol Med 1973;143:723–5.PubMedGoogle Scholar
  7. 7.
    Keyzer JJ, Ousting E, Wolthers BG, Muskiet FAJ, Hindriks FR, Van der Slik W. Zinc in plasma and serum: influence of contamination due to the collection tubes. Pharm Weekbl [Sci] 1983;5:248–51.Google Scholar
  8. 8.
    Riordan JF, Vallee BL. Structure and function of zinc metalloenzymes. In: Prasad AS, Oberleas D, eds. Trace elements in human health and disease. Vol. 1, Zinc and copper. New York: Academic Press, 1976:227–56.Google Scholar
  9. 9.
    Kiilerich S, Christensen MS, Naestoft J, Christiansen C. Determination of zinc in serum and urine by atomic absorption spectrophotometry; relationship between serum levels of zinc and proteins in 104 normal subjects. Clin Chim Acta 1980;105:231–9.CrossRefPubMedGoogle Scholar

Copyright information

© Bohn, Scheltema & Holkema 1983

Authors and Affiliations

  • J. J. Keyzer
    • 1
  • E. Oosting
    • 1
  • B. G. Wolthers
    • 1
  • F. A. J. Muskiet
    • 1
  1. 1.Central Laboratory for Clinical ChemistryUniversity HospitalRB GroningenThe Netherlands

Personalised recommendations