Zinc in plasma and serum: influence of contamination due to the collection tubes
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The contamination caused by rubber stoppers of collection tubes preceding the determination of zinc in plasma and serum was investigated. The use of evacuated blood collection tubes (EBC-tubes), normally used for the collection of serum samples, could give rise to an average artificial increase of normal serum zinc concentrations of about 250%. Heparine containingebc-tubes, used for the collection of plasma, and plainebc-tubes of an experimental production appeared to be suitable for correct zinc determinations. There was no difference between the serum and plasma zinc levels of fifty volunteers.
KeywordsZinc Serum Sample Stopper Normal Serum Blood Collection
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- 1.Riordan JF, Vallee BL. Structure and function of zinc metalloenzymes. In: Prasad AS, Oberleas D, eds. Trace elements in human health and disease, Vol. 1: Zinc and copper. New York: Academic Press, 1976:227–56.Google Scholar
- 3.Sommer AL, Lipman CB. Evidence on the indispensable nature of zinc and boron for higher green plants. Plant Phys 1926;1:231–49.Google Scholar
- 4.Underwood EJ. Trace elements in human and animal nutrition. 4th ed. New York: Academic Press, 1977.Google Scholar
- 8.Elmes M, Golden MK, Love AHG. Unresponsive coeliac disease. Q J Med 1976;45:696–7.Google Scholar
- 15.Deming WE. Statistical adjustment of data. New York: John Wiley & Sons, Ltd., 1943:184.Google Scholar
- 17.Casey CE, Hambidge KM. Epidemiological aspects of human zinc deficiency. In: Nriagu JO, ed. Zinc in the environment, part II: Health effects. New York: John Wiley & Sons, Ltd., 1980.Google Scholar