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Pharmaceutisch Weekblad

, Volume 2, Issue 1, pp 280–281 | Cite as

The analytical consequence of the decomposition of prednisolone to 17-deoxyprednisolone in stability control

  • D. Dekker
Short Communications
  • 23 Downloads

Abstract

17-Deoxyprednisolone, a decomposition product of prednisolone, interferes in some stability-indicating spectrophotometric methods for corticosteroids. The false positive reaction of 17-deoxyprednisolone with tetrazolium blue and with the method ofBundgaard andHansen (1979), is discussed.

Keywords

Public Health Internal Medicine Corticosteroid Prednisolone Tetrazolium 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Bohn, Scheltema & Holkema 1980

Authors and Affiliations

  • D. Dekker
    • 1
  1. 1.Department of Analytical Pharmacy, Faculty of PharmacyState University of UtrechtGH UtrechtThe Netherlands

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