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Pharmaceutisch Weekblad

, Volume 2, Issue 1, pp 262–265 | Cite as

Determination of free acid and anhydride content in aliphatic and aromatic cyclic anhydrides by conductometric titration

  • S. J. Sie-Tjoeng
  • H. J. De Jong
Original Articles
  • 95 Downloads

Abstract

The simultaneous determination of free acid and anhydride content in samples of cyclic aliphatic and aromatic anhydrides was studied. Conductometric titration with methanolic sodium methoxide while using acetone as a solvent proves to be a reliable method, applicable to small amounts of sample (0.3 mmol). The results of the conductometric method were checked by potentiometric titration of free acid with trinonylamine, and by determination of the total acid content after complete hydrolysis of the sample.

Keywords

Sodium Acetone Anhydride Acid Content Reliable Method 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Bohn, Scheltema & Holkema 1980

Authors and Affiliations

  • S. J. Sie-Tjoeng
    • 1
  • H. J. De Jong
    • 1
  1. 1.Department of Pharmaceutical Analysis and Analytical Chemistry, Subfaculty of Pharmacy, Gorleaus LaboratoriaState UniversityLeidenThe Netherlands

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