Pharmaceutisch Weekblad

, Volume 10, Issue 6, pp 277–280 | Cite as

Screening of some essential oils for their activities on dermatophytes

  • A. M. Janssen
  • J. J. C. Scheffer
  • A. W. Parhan-Van Atten
  • A. Baerheim Svendsen
Original Articles


Fifty-three essential oils were tested against three frequently occurring dermatophytes (Epidermophyton floccosum, Trichophyton mentagrophytes var.interdigitale, T. rubrum) by means of an agar dilution technique. The oils were selected at random and not on the basis of a supposed activity. A number of oils showed interesting activities, expressed as maximum inhibitory dilution values, against the dermatophytes used. At the highest dilution tested (1:3,200, vol/vol), one out of six oils was active againstT. mentagrophytes var.interdigitale, and one out of three to four oils was active against the other dermatophytes.


Agar dilution technique Antimycotics Dermatophytes Drug screening Essential oils Statistics 


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Copyright information

© Bohn, Scheltema & Holkema 1988

Authors and Affiliations

  • A. M. Janssen
    • 1
  • J. J. C. Scheffer
    • 1
  • A. W. Parhan-Van Atten
    • 1
  • A. Baerheim Svendsen
    • 1
  1. 1.Division of Pharmacognosy, Center for Bio-Pharmaceutical SciencesLeiden University, Gorlaeus LaboratoriesRA Leidenthe Netherlands

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