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Pharmacy World and Science

, Volume 15, Supplement 1, pp 34–36 | Cite as

Stability of cisplatin in sodium chloride 0.9% intravenous solution related to the container's material

  • Montserrat Pujol Cubells
  • Josefina Prat Aixela
  • Victòria Girona Brumos
  • Salvador Duran Pou
  • Miquel Villaronga Flaque
Practice/Case Reports

Abstract

The stability of cisplatin in sodium chloride 0.9% intravenous solutions contained in glass bottles, polyvinyl chloride bags, polyethylene and polypropylene containers was studied over two weeks. The solubility of cisplatin at 4°C was also studied for possible precipitation. The type of container had no effect on cisplatin decomposition. No precipitation at 4°C was observed within the time period studied.

Keywords

Cisplatin Drug stability Glass Injections, intravenous Polyethylene Polypropylene Polyvinyl chloride Precipitation 

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Copyright information

© Periodicals Service Company 1993

Authors and Affiliations

  • Montserrat Pujol Cubells
    • 1
  • Josefina Prat Aixela
    • 1
  • Victòria Girona Brumos
    • 1
  • Salvador Duran Pou
    • 2
  • Miquel Villaronga Flaque
    • 2
  1. 1.Faculty of Pharmacy, Department of PharmacyAvgd. Diagonal s/nBarcelonaSpain
  2. 2.Pharmacy DepartmentHospital general de la Vall d'HebronBarcelonaSpain

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