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Pharmaceutisch Weekblad

, Volume 5, Issue 6, pp 269–280 | Cite as

Immunoglobulins as targeting agents for liposome encapsulated drugs

  • P. A. H. M. Toonen
  • D. J. A. Crommelin
Review Articles

Abstract

Recent literature dealing with the immunoglobulin-liposome combination as a tool for drug targeting is reviewed. Mechanisms for binding of immunoglobulins to liposomes are discussed. Results obtained so far by using this concept both to induce specific liposome-cell interactions inin vitro cell cultures and to target drug containing liposomes to selected tissues in animal studies are evaluated.

Keywords

Public Health Cell Culture Internal Medicine Animal Study Recent Literature 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Abra, R.M., andC.A. Hunt (1981)Biochim. Biophys. Acta 666, 493–503.Google Scholar
  2. Barbet, J., P. Machy andL.D. Leserman (1981)J. Supramol. Struct. Cell. Biochem. 16, 243–258.Google Scholar
  3. Ellens, H. (1982)Liposomes as drug carriers in cancer chemotherapy. Ph.D. Thesis, Groningen.Google Scholar
  4. Endoh, H., Y. Suzuki andY. Hashimoto (1981)J. Immunol. Methods 44, 79–85.Google Scholar
  5. Fildes, F.J.T. (1981) In:Liposomes: from physical structure to therapeutic applications (Knight C.G., Ed.). Elsevier/ North-Holland, Amsterdam, 465–485.Google Scholar
  6. Finkelstein, M.G., S.H. Kuhn, H. Schieren, G. Weissmann andS. Hoffstein (1981)Biochim. Biophys. Acta 673, 286–302.Google Scholar
  7. Froese, G., I. Berczi andL.G. Israels (1982)Immunology 45, 313–323.Google Scholar
  8. Gregoriadis, G. (1979)Drug carriers in biology and medicine. Academic Press, London, 287–341.Google Scholar
  9. Gregoriadis, G. (1982)Drugs 24, 261–266.Google Scholar
  10. Gregoriadis, G., andA.C. Allison (1980)Liposomes in biological systems. John Wiley & Sons, Chichester.Google Scholar
  11. Gregoriadis, G., andA. Meehan (1981)Biochem. J. 200, 211–216.Google Scholar
  12. Gregoriadis, G., andE.D. Neerunjun (1975)Biochem. Biophys. Res. Commun. 65, 537–544.Google Scholar
  13. Gregoriadis, G., D.E. Neerunjun andR. Hunt (1977)Life Sci. 21, 357–370.Google Scholar
  14. Gregoriadis, G., C. Kirby, A. Meehan andJ. Senior (1981a)Drugs and immunocompetent cell functions (Nicolau, C., andA. Paraf, Eds.) Academic Press, London, 29–51.Google Scholar
  15. Gregoriadis, G., A. Meehan andM.M. Mah (1981b)Biochem. J. 200, 203–210.Google Scholar
  16. Gregoriadis, G., J. Senior andA. Trouet (1982)Targeting of drugs. Plenum Press, New York.Google Scholar
  17. Harsch, M., P. Walther andH.G. Weder (1981)Biochem. Biophys. Res. Commun. 103, 1069–1076.Google Scholar
  18. Heath, T.D., R.T. Fraley andD. Papahadjopoulos (1980)Science 210, 539–541.Google Scholar
  19. Heath, T.D., B.A. Macher andD. Papahadjopoulos (1981)Biochim. Biophys. Acta 640, 66–81.Google Scholar
  20. Heath, T.D., J.A. Montgomery, J.R. Riper andD. Papahadjopoulos (1983)Proc. Nat. Acad. Sci. USA 80, 1377–1381.Google Scholar
  21. Huang, L., andS.J. Kennel (1979)Biochemistry 18, 1702–1707.Google Scholar
  22. Huang, A., L. Huang andS.J. Kennel (1980)J. Biol. Chem. 255, 8015–8018.Google Scholar
  23. Huang, A., S.J. Kennel andL. Huang (1981)J. Immunol. Methods 44, 79–85.Google Scholar
  24. Huang, A., Y.S. Tsao, S.J. Kennel andL. Huang (1982)Biochim. Biophys. Acta 716, 140–150.Google Scholar
  25. Hutchcraft, G.L. (1980)Diss. Abstr. Int. B 41 74-B.Google Scholar
  26. Jansons, V.K., andP.L. Mallett (1981)Anal. Biochem. 111, 54–59.Google Scholar
  27. Juliano, R.L. (1982) In:Targeting of drugs (Gregoriadis, G., J. Senior andA. Trouet, Eds.). Plenum Press, New York, 285–300.Google Scholar
  28. Juliano, R.L., D. Stamp andN. Mccullough (1978).Ann. N.Y. Acad. Sci.308, 411–423.Google Scholar
  29. Kaye, S.B. (1981)Cancer Treat. Rev. 8, 27–50.Google Scholar
  30. Kaye, S.B., andV.J. Richardson (1979)Cancer Chemother. Pharmacol. 3, 81–85.Google Scholar
  31. Knight, C.G. (1981)Liposomes: from physical structure to therapeutic applications. Elsevier/North Holland Biomedical Press, Amsterdam.Google Scholar
  32. Leserman, L.D. (1981) In:Liposomes, drugs and immunocompetent cell functions (Nicolau, C., andA. Paraf, Eds.). Academic Press, London, 109–122.Google Scholar
  33. Leserman, L.D., J. Barbet andF. Kourilsky (1980)Nature 288, 602–604.Google Scholar
  34. Leserman, L.D., P. Machy andJ. Barbet (1981)Nature 293, 226–228.Google Scholar
  35. Machy, P., M. Pierres, J. Barbet andL.D. Leserman (1982a)J. Immunol. 129, 2098–2102.Google Scholar
  36. Machy, P., J. Barbet andL.D. Leserman (1982b)Proc. Nat. Acad. Sci. USA 79, 4148–4152.Google Scholar
  37. Martin, F.J., andD. Papahadjopoulos (1982)J. Biol. Chem. 257, 286–288.Google Scholar
  38. Martin, F.J., W.L. Hubbell andD. Papahadjopoulos (1981)Biochemistry 20, 4229–4238.Google Scholar
  39. Marx, J.L. (1982)Science 216, 283–285.Google Scholar
  40. Nicolau, C., andA. Paraf (1981)Liposomes, drugs and immunocompetent cell functions. Academic Press, London.Google Scholar
  41. Papahadjopoulos, D., Ed. (1978)Ann. N.Y. Acad. Sci. 308.Google Scholar
  42. Papahadjopoulos, D., T. Heath, F. Martin, R. Fraley andR. Straubinger (1982) In:Targeting of drugs (Gregoriadis, G., J. Senior andA. Trouet, Eds.). Plenum Press, New York, 375–391.Google Scholar
  43. Poste, G. (1983)Biol. Cell 47, 19–38.Google Scholar
  44. Rahman, Y.E., E.A. Cenry, K.R. Patel, E.H. Lau andB.J. Wright (1982)Life Sci. 31, 2061–2071.Google Scholar
  45. Roerdink, F., J. Dijkstra, G. Hartman, B. Bolscher andG. Scherphof (1981)Biochim. Biophys. Acta 677, 79–89.Google Scholar
  46. Roitt, I.M. (1980)Essential Immunology, 4th Ed. Blackwell Scientific Publications, Oxford.Google Scholar
  47. Ryman, B.E., andD.A. Tyrrell (1979) In:Liposomes in biology and pathology (Dingle, J.T., P.J. Jacques andI.H. Shaw, Eds.). North-Holland Publishing Company, Amsterdam, 549–574.Google Scholar
  48. Scherphof, G., F. Roerdink, D. Hoekstra, J. Zborowski andE. Wisse (1980) In:Liposomes in biological systems (Gregoriadis, G., andA.C. Allison, Eds.). John Wiley & Sons Ltd., New York, 179–209.Google Scholar
  49. Schreier, H., (1982)Pharm. unserer Zeit 11, 97–102.Google Scholar
  50. Schreier, H., andM. Raeder-Schikorr (1982)Pharm. unserer Zeit 11, 103–108.Google Scholar
  51. Schwendener, R.A., M. Asanger andH.G. Weder (1981)Biochem. Biophys. Res. Commun. 100, 1055–1062.Google Scholar
  52. Shen, D.F., A. Huang andL. Huang (1982)Biochim. Biophys. Acta 689, 31–37.Google Scholar
  53. Sinha, D., andF. Karush (1982)Biochim. Biophys. Acta 684, 187–194.Google Scholar
  54. Szoka, F., andD. Papahadjopoulos (1981) In:Liposomes: from physical structure to therapeutic applications (Knight, C.G., Ed.). Elsevier/North -Holland, Amsterdam, 51–82.Google Scholar
  55. Torchilin, V.P.,andA.L. Klibanov (1981)Enzyme Microb. Technol. 3, 297–304.Google Scholar
  56. Torchilin, V.P., B.A. Khaw, V.N. Smirnov andE. Haber (1979)Biochem. Biophys. Res. Commun. 89, 1114–1119.Google Scholar
  57. Urdal, D.L., andS. Hakomori (1980)J. Biol. Chem. 255 10509–10515.Google Scholar
  58. Vandenbranden, M., J.L. De Coen, R. Jeener, L. Kanarek andJ.M. Ruyschaert (1981)Mol. Immunol. 18, 621–631.Google Scholar
  59. Van Rooijen, N., andR. Van Nieuwmegen (1980a)Cell Immunol. 49, 402.Google Scholar
  60. Van Rooijen, N., andR. Van Nieuwmegen (1980b)Immunol. Commun. 9, 243.Google Scholar
  61. Van Rooijen, N., andR. Van Nieuwmegen (1980c)Immunol. Commun. 9, 747.Google Scholar
  62. Van Rooijen, N., andR. Van Nieuwmegen (1982) In:Targeting of drugs (Gregoriadis, G., J. Senior andA. Trouet, Eds.). Plenum Press, New York, 301–326.Google Scholar
  63. Widder, K.J., A.E. Senyei andB. Sears (1982)J. Pharm. Sci. 71, 379–386.Google Scholar
  64. Yatvin, M.B. (1982)Med. Phys. 9, 149–175.Google Scholar
  65. Zumbuehl, O., andH.G. Weder (1981)Biochim. Biophys. Acta 640, 252–262.Google Scholar

Copyright information

© Royal Dutch Association for Advancement of Pharmacy 1983

Authors and Affiliations

  • P. A. H. M. Toonen
    • 1
  • D. J. A. Crommelin
    • 1
  1. 1.Department of Pharmaceutics, Pharmaceutical LaboratoryUniversity of UtrechtGH UtrechtThe Netherlands

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