Advertisement

Experientia

, Volume 36, Issue 1, pp 98–99 | Cite as

A novel effect of cobalt treatment on calcium-dependent responses of the cockroach salivary gland

  • Mary R. Mitchell
  • B. L. Ginsborg
  • C. R. House
Specialia

Summary

After incubation in calcium-free solutions containing cobalt, the readmission of calcium caused prolonged but reversible hyperpolarization of acinar cells of cockroach salivary glands and prolonged fluid secretion. It is suggested that cobalt treatment increases the permeability of the acinar cell membrane to calcium.

Keywords

Calcium Permeability Cell Membrane Cobalt Salivary Gland 

References

  1. 2.
    J.N. Weakly, J. Physiol., Lond.234, 597 (1973).CrossRefGoogle Scholar
  2. 3.
    S. Hagiwara and K. Takahashi, J. gen. Physiol.50, 583 (1967).CrossRefGoogle Scholar
  3. 4.
    P.F. Baker, Symp. Soc. exp. Biol.30, 67 (1976).Google Scholar
  4. 5.
    R. Hammerschlag, A.Y. Chiu and C.R. Dravid, Brain Res.114, 353 (1976).CrossRefGoogle Scholar
  5. 6.
    J.G. Blackman, B.L. Ginsborg and C.R. House, J. Physiol., Lond.287, 67 (1979).CrossRefGoogle Scholar
  6. 7.
    O.H. Petersen and G.L. Pedersen, J. Membrane Biol.16, 353 (1974).CrossRefGoogle Scholar
  7. 8.
    F. Bowser-Riley, C.R. House and R.K. Smith, J. Physiol., Lond.279, 473 (1978).CrossRefGoogle Scholar
  8. 9.
    B.L. Ginsborg, C.R. House and E.M. Silinsky, J. Physiol., Lond.236, 723 (1974).CrossRefGoogle Scholar
  9. 10.
    R.W. Meech and F. Strumwasser, Fedn Proc.29, 834 (1970).Google Scholar
  10. 11.
    P.J. Romero and R. Whittam, J. Physiol. Lond.214, 481 (1971).CrossRefGoogle Scholar
  11. 12.
    R.K. Smith and C.R. House, Experientia33, 1182 (1977).CrossRefGoogle Scholar
  12. 13.
    W.W. Douglas and R.P. Rubin, J. Physiol. Lond.159, 40 (1961).CrossRefGoogle Scholar
  13. 14.
    W.W. Douglas and A.M. Poisner, J. Physiol. London.165, 528 (1963).CrossRefGoogle Scholar
  14. 15.
    O.H. Petersen and N. Ueda, J. Physiol. Lond.254, 583 (1976).CrossRefGoogle Scholar
  15. 16.
    M.J. Berridge, B.D. Lindley and W.T. Prince, J. Physiol. Lond.244, 549 (1975).CrossRefGoogle Scholar
  16. 17.
    M.J. Berridge, B.D. Lindley and W.T. Prince, J. exp. Biol.62, 629 (1975).PubMedGoogle Scholar

Copyright information

© Birkhäuser Verlag 1980

Authors and Affiliations

  • Mary R. Mitchell
    • 1
    • 2
  • B. L. Ginsborg
    • 1
    • 2
  • C. R. House
    • 1
    • 2
  1. 1.Department of PharmacologyUniversity Medical SchoolEdinburgh
  2. 2.Department of Veterinary PhysiologyUniversity of EdinburghEdinburghScotland

Personalised recommendations