Human neuropharmacological findings with oxapadol (MD 720111), a new non-narcotic analgesic
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The effects of oxapadol, a new non-narcotic analgesic, were tested in man using the electrically-induced nociceptive flexion reflex in the flexor muscles of the lower limb as an index of pain. The drug caused a significant increase in the threshold of the reflex whereas no change was noted with placebo.
KeywordsPlacebo Flexor Muscle Nociceptive Flexion
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