Pharmaceutisch Weekblad

, Volume 11, Issue 4, pp 132–133 | Cite as

The place of quinolones in the treatment of respiratory tract infections

  • J. W. M. van der Meer
Therapeutic Interventions in Lower Respiratory Tract Infections


The new quinolones are rarely indicated for the treatment of community-acquired pneumonia in the normal host. For nosocomial pneumonia they may be used when a Gram-negative aerobic bacillus is the causative organism. Pneumonia in the compromised host may be an indication for a quinolone. In the hypogammaglobulinaemic patient withHaemophilus influenzae pneumonia, the quinolones may be used, especially when the organism is resistant to other drugs. For the neutropenic patient with Gram-negative pneumonia the quinolones may be a good choice. However, more clinical studies are needed. In treatment for exacerbations of chronic bronchitis, failures seem to be associated with pneumococcal infections. For patients with cystic fibrosis, the quinolones offer successful ambulatory treatment for theirPseudomonas andHaemophilus infections. The information regarding dosage schedules is still incomplete.


Bronchitis Cross infection Immunocompromised host Pneumonia Quinolones 


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Copyright information

© Royal Dutch Association for Advancement of Pharmacy 1989

Authors and Affiliations

  • J. W. M. van der Meer
    • 1
  1. 1.Division of General Internal MedicineUniversity Hospital NijmegenHB Nijmegenthe Netherlands

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