Pharmaceutisch Weekblad

, Volume 13, Issue 1, pp 7–12 | Cite as

Pharmacology of long-term potentiation

A model for learning reviewed
  • Margot Beukers
  • Erik W. G. M. Boddeke


Long-term potentiation is widely used as a model for memory formation. Recently, much information concerning this topic like the involvement of protein kinase C, arachidonic acid andN-methyl-d-aspartate receptors has been reported. In this review recent discoveries concerning long-term potentiation and the pharmacological implications for the development of cognition-enhancing drugs are discussed.


Drugs Memory, long-term Pharmacology 


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Copyright information

© Royal Dutch Association for Advancement of Pharmacy 1991

Authors and Affiliations

  • Margot Beukers
    • 1
  • Erik W. G. M. Boddeke
    • 2
  1. 1.Division of Medicinal ChemistryGorlaeus LaboratoriesRA LeidenThe Netherlands
  2. 2.Sandoz PharmaSandoz Preclinical ResearchBasleSwitzerland

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