Pharmaceutisch Weekblad

, Volume 14, Issue 3, pp 98–100 | Cite as

Enzymes involved in the metabolism of valproate

  • J. Hulsman
Recent Developments on Valproate and its Metabolites


This article provides a short overview of enzymes involved in activation, transport and oxidation (β andω) of valproate and other fatty acids.


Biodegradation Enzymes Valproic acid 


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  1. 1.
    Hulaman JARJ. Hyperammonemia and the use of antiepileptic drugs including valproate. In: Fourth International Symposium on Sodium Valproate and Epilepsy. London: Royal Society of Medicine Services 1985:163–9.Google Scholar

Copyright information

© Royal Dutch Association for Advancement of Pharmacy 1992

Authors and Affiliations

  • J. Hulsman
    • 1
  1. 1.Centre for Bio-Pharmaceutical SciencesRA Leidenthe Netherlands

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