Pharmaceutisch Weekblad

, Volume 5, Issue 2, pp 74–76 | Cite as

Comparison of lung deposition of a solution after nebulization by three commonly used portable nebulizers

  • R. A. Foulds
  • L. O. M. J. Smithuis
Short Communications


The efficacy of small portable nebulizers is often assumed by patients, pharmacists and physicians. Three healthy volunteers inhaled a mixture of sodium cromoglycate solution mixed with aqueous technetium-99 nebulized by each of three nebulizers and the distribution of radioactivity was detected by gamma scintigraphy. Unexpectedly large differences in the total amount of tracer delivered to the lungs were detected. The possible mechanisms and implications are discussed but it is clear that more information on the performance of individual nebulizers should be available.


Public Health Sodium Internal Medicine Healthy Volunteer Cromoglycate 
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Copyright information

© Royal Dutch Association for Advancement of Pharmacy 1983

Authors and Affiliations

  • R. A. Foulds
    • 1
  • L. O. M. J. Smithuis
    • 2
  1. 1.Fisons BVAM LeusdenThe Netherlands
  2. 2.Department of Nuclear MedicineSt. Lambertus HospitalAB HelmondThe Netherlands

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