Acta Neurochirurgica

, Volume 139, Issue 4, pp 286–294 | Cite as

EBIC-Guidelines for management of severe head injury in adults

  • A. I. R. Maas
  • M. Dearden
  • G. M. Teasdale
  • R. Braakman
  • F. Cohadon
  • F. Iannotti
  • A. Karimi
  • F. Lapierre
  • G. Murray
  • J. Ohman
  • L. Persson
  • F. Servadei
  • N. Stocchetti
  • A. Unterberg
Clinical Articles


Guidelines for the management of severe head injury in adults as evolved by the European Brain Injury Consortium are presented and discussed. The importance of preventing and treating secondary insults is emphasized and the principles on which treatment is based are reviewed. Guidelines presented are of a pragmatic nature, based on consensus and expert opinion, covering the treatment from accident site to intensive care unit. Specific aspects pertaining to the conduct of clinical trials in head injury are highlighted. The adopted approach is further discussed in relation to other approaches to the development of guidelines, such as evidence based analysis.


Brain injury intensive care secondary insults clinical trials 


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Copyright information

© Springer-Verlag 1997

Authors and Affiliations

  • A. I. R. Maas
    • 1
  • M. Dearden
    • 2
  • G. M. Teasdale
    • 3
  • R. Braakman
    • 4
  • F. Cohadon
    • 5
  • F. Iannotti
    • 6
  • A. Karimi
    • 7
  • F. Lapierre
    • 8
  • G. Murray
    • 9
  • J. Ohman
    • 10
  • L. Persson
    • 11
  • F. Servadei
    • 12
  • N. Stocchetti
    • 13
  • A. Unterberg
    • 14
  1. 1.Department of NeurosurgeryUniversity Hospital RotterdamRotterdamThe Netherlands
  2. 2.Anaesthetic DepartmentLeeds General InfirmaryLeedsUK
  3. 3.Department of NeurosurgeryInstitute of Neurological Sciences, The Southern General HospitalGlasgowUK
  4. 4.Berkel EnschotThe Netherlands
  5. 5.Department of NeurosurgeryHôspital PellegrinBordeauxFrance
  6. 6.Department of NeurosurgerySouthhampton General HospitalSouthamptonUK
  7. 7.Neurochirurgische KlinikUniversität zu Köln, KölnGermany
  8. 8.Service de NeurochirurgieHospital Jean BernardPoitiersFrance
  9. 9.Medical Statistics UnitUniversity of Edinburgh, Medical SchoolEdinburghUK
  10. 10.Department of NeurosurgeryHelsinki University Central HospitalHelsinkiFinland
  11. 11.Department of NeurosurgeryAkademiska HospitalUppsalaSweden
  12. 12.Cesena SoccorsoOspedale “M. Bufalini”Cesena (FO)Italy
  13. 13.Terapia Intensiva NeurochirurgicaPad. Beretta Neuro/Ospedale PoliclinicoMilanoItaly
  14. 14.Department of NeurosurgeryVirchow-Klinikum, Medizinische Fakultät der Humboldt Universität zu BerlinBerlinGermany

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