Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Synthesen von Heterocyclen, 122. Mitt.: Über die Reaktion des Perimidons mit aktiven Malonestern

Syntheses of heterocycles, CXXII: Reaction of perimidone with reactive malonates

  • 23 Accesses

  • 1 Citations

Zusammenfassung

Perimidon (1) reagiert mit monosubstit. Malonsäure-trichlorphenylestern (2) bei 250° zu 9-Hydroxy-5,7-dioxo-4,5-dihydro-7H-pyrido[1,2,3-cd]perimidinen (3), die durch saure Hydrolyse zu 10-Amino-4-hydroxy-benzo[h]carbostyrilen (4) gespalten werden.

Abstract

Perimidone (1) reacts with monosubstituted 2.4.6-trichlorophenyl malonates at 250° to 9-hydroxy-5.7-dioxo-4.5-dihydro-7H-pyrido[1.2.3-cd]perimidines (3), which are cleaved by acid yielding 10-amino-4-hydroxy-benzo[h]quinolin-2-ones (4).

This is a preview of subscription content, log in to check access.

Author information

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Kappe, T., Ziegler, E. & Chirazi, M.A.A. Synthesen von Heterocyclen, 122. Mitt.: Über die Reaktion des Perimidons mit aktiven Malonestern. Monatshefte für Chemie 100, 142–145 (1969). https://doi.org/10.1007/BF00938249

Download citation