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New spin-labeled biologically active compounds

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  • 4 Citations

Conclusions

  1. 1.

    The paramagnetic derivatives of diethylenimino-S-triazine, pentaethyleniminocyclotriphospha-zatriene, and p-N-di-(β-chloroethyl)aminophenylacetic acid were synthesized.

  2. 2.

    The 4-aminomethyl- and 4-(β-aminoethyl)-2, 2, 6,6-tetramethylpiperidine-1-oxyls were synthesized.

  3. 3.

    A study was made of the reaction of the new spin-labeled compounds with DNA, synthetic polynucleotides, and albumin.

  4. 4.

    A study was made of the τsec of the spin-labeled polynucleotides as a function of the action of deoxyribonuclease, temperature, and the formation of purine-pyrimidine complexes.

  5. 5.

    The paramagnetic ethers of cellulose were obtained by the condensation of alkali cellulose with the paramagnetic derivatives of dichloro- and diethyleniminotriazine, and also of pentaethyleniminocyclo-triphosphazatriene.

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Literature cited

  1. 1.

    N. P. Konovalova, G. N. Bogdanov, V. B. Miller, M. B. Neiman, É. G. Rozantsev, and N. M. Émanuél, Dokl. Akad. Nauk SSSR,157, 707 (1964).

  2. 2.

    A. B. Shapiro, V. I. Suskina, B. V. Rozynov, and É. G. Rozantsev, Izv. Akad. Nauk SSSR, Ser. Khim., 2828 (1969).

  3. 3.

    A. B. Shapiro, A. A. Kropacheva, V. I. Suskina, and É. G. Rozantsev, USSR Patent 322060 (1971); Byull. Izobr., No. 12 (1973).

  4. 4.

    A. B. Shapiro, A. A. Kropacheva, V. I. Suskina, B. V. Rozynov, and É. G. Rozantsev, Izv. Akad. Nauk SSSR, Ser. Khim., 864 (1971).

  5. 5.

    G. Sosnovsky, Z. Naturforsch.,28c, 781 (1973).

  6. 6.

    N. P. Konovalova, R. F. D'yachkovskaya, and E. G. Kiseleva, Voprosy Onkologii,30, 581 (1973).

  7. 7.

    A. Ya. Berlin and L. S. Yaguzhinskii, Usp. Khim.,34, 1293 (1965).

  8. 8.

    V. V. Vlasov, N. I. Grineva, and D. G. Knorre, Izv. Sibirsk. Otd. Akad. Nauk SSSR, Ser. Khim. Nauk, No. 2, 1041 (1969).

  9. 9.

    L. S. Yaguzhinskii and A. D. Chinaeva, Zh. Obshch. Khim.,39, 2581 (1969).

  10. 10.

    G. I. Likhtenshtein, Method of Spin Labels in Molecular Biology fin Russian], Khimiya (1974).

  11. 11.

    A. B. Shapiro, L. B. Lebedeva, V. I. Suskina, G. N. Antipina, L. N. Smirnov, P. I. Levin, and É. G. Rozantsev, Vysokomolekul. Soedin.,A15, 2673 (1973).

  12. 12.

    V. A. Radtsig, A. B. Shapiro, and É. G. Rozantsev, Vysokomolekul. Soedin.,B14, 685 (1972).

  13. 13.

    A. B. Shapiro, K. Baimagambetov, V. A. Radtsig, and É. G. Rozantsev, Vysokomolekul. Soedin.,B15, 300 (1973).

  14. 14.

    G. I. Likhtenshtein and P. Kh. Bobodzhanov, Biofizika,4, 741 (1969).

  15. 15.

    A. A. Kropacheva and N. M. Kashnikova, Zh. Obshch. Khim.,35, 1988 (1965).

  16. 16.

    L. E. Sventsitskaya, A. A. Kropacheva, and S. I. Sergievskaya, Zh. Obshch. Khim.,28, 1601 (1958).

  17. 17.

    A. A. Kropacheva and N. M. Kashnikova, Zh. Obshch. Khim.,38, 136 (1968).

  18. 18.

    J. Warren, J. D. Reid, and C. Hamalainen, Text. Res.,22, 584 (1952).

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Additional information

Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 9, pp. 2077–2082, September, 1975.

The authors express their gratitude to B. V. Rozynov for taking the mass spectra.

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Shapiro, A.B., Bogach, L.S., Chumakov, V.M. et al. New spin-labeled biologically active compounds. Russ Chem Bull 24, 1959–1964 (1975). https://doi.org/10.1007/BF00930174

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Keywords

  • Ether
  • Cellulose
  • Albumin
  • Active Compound
  • Dichloro