Mice were immunized against challenge withHymenolepis diminuta by feeding cysticercoids or by surgically implanting into the duodenum strobilate worms of different ages. Young worms stimulate stronger immunity than older ones, although the latter presents the host with a greater amount of strobilar tissue per unit time. An increase in the number of immunizing worms is associated with an increase in the level of protection. It is concluded that the development of functional immunity againstH. diminuta in mice has both quantitative and qualitative antigenic requirements; it is influenced by worm age and is independent of worm mass.
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Andreassen J, Hindsbo O, Ruitenberg EJ (1978)Hymenolepis diminuta infections in congenitally athymic (nude) mice: Worm kinetics and intestinal histopathology. Immunology 34:105–113
Befus AD (1975) Secondary infections ofHymenolepis diminuta in mice: Effects of varying worm burdens in primary and secondary infections. Parasitology 71:61–75
Christie PR (1978) The roles of the scolex and the strobila in stimulating the immune response of the mouse toHymenolepis diminuta. Parasitology 77 (3):XXV
Colquhoun D (1971) Lectures on biostatistics. Clarendon Press, Oxford, pp 402–403
Elowni EE (1980) Immunity to tapeworms: Vaccination againstHymenolepis diminuta and role of the bursa of Fabricius in rejection ofRaillietina cesticillus. Ph D thesis, University of Glasgow
Elowni EE (1982a)Hymenolepis diminuta: The origin of protective antigens. Exp Parasitol 53:157–163
Elowni EE (1982b)Hymenolepis diminuta: Source of protective antigens as determined by irradiation and chemical elimination of immunizing worms. Exp Parasitol 54:1–6
Hopkins CA, Barr IF (1982) The source of antigen in an adult tapeworm. Int J Parasitol 12:327–333
Hopkins CA, Zajac A (1976) Transplantation ofHymenolepis diminuta into naive, immune and irradiated mice. Parasitology 73:73–81
Hopkins CA, Subramanian G, Stallard H (1972a) The effect of immunosuppressants on the development ofHymenolepis diminuta in mice. Parasitology: 65:111–120
Hopkins CA, Subramanian G, Stallard H (1972b) The development ofHymenolepis diminuta in primary and secondary infections in mice. Parasitology 64:401–412
Siegel S (1956) Non-parametric statistics for the behavioral sciences. McGraw-Hill, New York, pp 104–110
Weinmann CJ (1966) Immunity mechanisms in cestode infections. In: Soulsby EJL (ed) Biology of Parasites. Academic Press, New York, London, pp 301–320
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Elowni, E.E. Hymenolepis diminuta: Immunogenicity of the strobilate worm. Z. Parasitenkd. 69, 501–505 (1983). https://doi.org/10.1007/BF00927706
- Functional Immunity
- Strong Immunity
- Young Worm
- Worm Mass
- Antigenic Requirement