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Transformed steroids

Communication 67. Aminomethylene derivatives of dehydropregnenolone acetate

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Conclusions

The enamination of the 21-hydroxymethylene derivative of the 16,17-dehydropregnenolone under conventional conditions is accompanied by the C-alkylation of the intermediate enamino ketone by a second molecule of the starting β-keto aldehyde.

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Literature cited

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    A. A. Akhrem, A. M. Moiseenkov, and V. V. Veselovskii, Khim. Geterotsikl. Soed., 1014 (1973).

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    N. J. Doorenbos and L. Milewich, J. Org. Chem.,31, 3193 (1966).

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Additional information

Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 2, pp. 431–434, February, 1974.

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Moiseenkov, A.M., Veselovskii, V.V. & Kamernitskii, A.V. Transformed steroids. Russ Chem Bull 23, 399–401 (1974). https://doi.org/10.1007/BF00924696

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Keywords

  • Steroid
  • Aldehyde
  • Ketone
  • Conventional Condition
  • Enamino Ketone