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Anatomical risk factors in primary angle-closure glaucoma

A ten year follow up survey based on limbal and axial anterior chamber depths in a high risk population

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Abstract

A population of 539 persons was examined in 1979, using LCD and ACD estimations acc. to van Herick et al. and by Haag Streit pachymetry, respectively. ACD had been measured already in 1969, due to a remarkable occurrence of primary angle-closure glaucoma (PACG) in the survey population of Greenland Eskimos (District of Uummannaq). The present follow up study in 1989 aimed at persons presently above age 40, who had showneither an LCD value graded as 0 (contact) or 1 (< 0.25 of corneal thickness=CT),or a value of 2 (=0.25 CT) if an ACD value of <=2.70mm (CT included) had also been found. PACG patients or suspects known in 1979 already were excluded from the present analyses. A total of 75 persons was now examined. Five had developed acute (n=2) or intermittent PACG (n=3)during the ten year period.At the survey 3 intermittent and 4 latent PACG cases were detected, yielding in ten years a PACG prevalence of 12/75=16% (sex ratio: M/F=2/10). One male case of severe secondary (partly inflammatory) ACG was also found. Past and present LCD and ACD values are given as well as gonioscopical status. Creeping, synechial angle-closure was frequent. Among probands who could not be examined, mostly due to death before 1989, 5/54 had developed PACG during the ten year period. Non-probands according to above criteria were mostly not examined. Yet their records were scrutinized for any event suspect of PACG. Thus among 258 persons above age 40 no PACG case was found.In conclusion: a fairly simple, anatomical slit lamp screening (of LCD and ACD) was found effectively to select a subgroup which proved to be at risk of PACG-development in the following ten year period.

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Abbreviations

ACD:

axial anterior chamber depth

LCD:

limbal anterior chamber depth

PACG:

primary angle-closure glaucoma

RE, LE:

right, left eye

References

  1. 1.

    Clemmesen V, Alsbirk PH. Primary angle-closure glaucoma (a.c.g.) in Greenland. Acta Ophthalmol (Kbh) 1971; 49: 47–58.

  2. 2.

    Alsbirk PH. Primary angle-closure glaucoma. Oculometry, epidemiology, and genetics in a high risk population. Acta Ophthalmol (Kbh) 1976; 54 (suppl 127): 1–31.

  3. 3.

    Drance SM. Angle-closure glaucoma among Canadian Eskimos. Can J Ophthalmol 1973; 8: 252–4.

  4. 4.

    Johnson GJ, Green JS, Paterson GD, Perkins ES. Survey of ophthalmic conditions in a Labrador community: II. Ocular disease. Can J Ophthalmol 1984; 19: 224–33.

  5. 5.

    Arkell SM, Lightman DA, Sommer A, Taylor HR, Korshin OM, Tielsch JM. The prevalence of glaucoma among Eskimos of Northwest Alaska. Arch Ophthalmol 1987; 105: 482–5.

  6. 6.

    van Rens GHMB, Arkell SM, Charlton W, Doesburg W. Primary angle-closure glaucoma among Alaskan Eskimos. Doc Ophthalmol 1988; 70: 265–76.

  7. 7.

    Loh RCK. The problem of glaucoma in Singapore. Singapore Med J 1968; 9: 76–80.

  8. 8.

    Hu Z, Zhao ZL, Dong FT et al. An epidemiologic investigation of glaucoma in Beijing Shun-yi County (Chinese). Chin J Ophthalmol 1989; 25: 115–8.

  9. 9.

    Alsbirk PH. Limbal and axial chamber depth variations. Acta Ophthalmol (Kbh) 1986; 64: 593–600.

  10. 10.

    Alsbirk PH. Early detection of primary angle-closure glaucoma. Limbal and axial chamber depth screening in a high risk population (Greenland Eskimos). Acta Ophthalmol (Kbh) 1988; 66: 556–64.

  11. 11.

    Alsbirk PH. Anterior chamber depth in Greenland Eskimos. I. A population study of variation with age and sex. Acta Ophthalmol (Kbh) 1974; 52: 551–64.

  12. 12.

    van Herick W, Shaffer RN, Schwartz A. Incidence and significance of the narrow angle. Am J Ophthalmol 1969; 68: 626–9.

  13. 13.

    Rosenberg T. Prevalence and causes of blindness in Greenland. Arct Med Res1987; 46: 13–7.

  14. 14.

    Lowe RF. Primary creeping angle-closure glaucoma. Br J Ophthalmol 1964; 48: 544–50.

  15. 15.

    Alsbirk PH, Clemmesen V. Primary angle-closure glaucoma and monocular blindness. Clinical pattern in 2 Inuit women from Greenland. Arct Med Res 1992; 51: 94–7.

  16. 16.

    Greve EC. Primary angle closure glaucoma. Extracapsular cataract extraction or filtering procedure? Internat Ophthalmol 1988; 12: 157–62.

  17. 17.

    Wishart PK, Atkinson PL. Extracapsular cataract extraction and posterior chamber lens implantation in patients with primary chronic angle-closure glaucoma; Effect on intraocular pressure control. Eye 1989; 3: 706–12.

  18. 18.

    Alsbirk PH. Optical pachymetry of anterior chamber. A methodological study of errors of measurement using Haag Streit 900 instruments. Acta Ophthalmol (Kbh) 1974; 52: 747–58.

  19. 19.

    Okabe I, Tomita G, Sugiyama K, Taniguchi T. An epidemiological study on the prevalence of the narrow chamber angle in Japanese (Japanese). Acta Soc Ophthalmol Jpn 1991; 95: 279–87.

  20. 20.

    Okabe I, Sugiyama K, Taniguchi T, Tomita G, Kitazawa Y. On factors related to the width of anterior chamber angle. Multivariate analysis of biometrically determined values. Acta Soc Ophthalmol Jpn 1991; 95: 486–94.

  21. 21.

    Zhao JL, Hu C. Relation between the depth of anterior chamber and anterior chamber angle on the pathogenesis of primary angle closure glaucoma. Afro-Asian J Ophthalmol 1988; 7: 84–8.

  22. 22.

    Congdon N, Wang F, Tielsch JM. Issues in the epidemiology and population-based screening of primary angle-closure glaucoma. Surv Ophthalmol 1992; 36: 411–23.

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Alsbirk, F.H. Anatomical risk factors in primary angle-closure glaucoma. Int Ophthalmol 16, 265–272 (1992). https://doi.org/10.1007/BF00917973

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Key words

  • anterior chamber depth
  • Greenland Eskimos
  • limbal chamber depth
  • primary angle-closure glaucoma
  • risk factors
  • screening