Monatshefte für Chemie - Chemical Monthly

, Volume 105, Issue 4, pp 863–868 | Cite as

Synthese von 2-Methylen-2,3-dihydro- und 2-Methyl-5H-thiazolo[3,2—a]thieno[2,3—d]pyrimidinen

  • F. Sauter
  • W. Deinhammer
  • K. Danksagmüller
Organische Chemie und Biochemie

Synthesis of 2-methylene-2,3-dihydro-and 2-methyl-5H-thiazolo[3.2—a]thieno[2.3—d]pyrimidines


The title substances and their [1]benzothieno analogues were synthesized by reaction of 3-allyl-2-mercapto-([1]benzo)thieno-[2.3—d]pyrimidine-4(3H)-ones with Br2 to 2-bromomethyl-2.3-dihydro-thiazolo[3.2—a]([1]benzo-)thieno[2.3—d]pyrimidine-5-ones, which on treatment with morpholine did not give the corresponding morpholine derivatives but elimination to the exocyclic double bond. These 2-methylene-2.3-dihydro-products were isomerized by H2SO4 to the corresponding 2-methyl compounds.


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Copyright information

© Springer-Verlag 1974

Authors and Affiliations

  • F. Sauter
    • 1
  • W. Deinhammer
    • 1
  • K. Danksagmüller
    • 1
  1. 1.Institut für Organische Chemie der Technischen Hochschule WienWienÖsterreich

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