Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Relation of structure to physiological action for phosphorylated chloral hemiacetals

  • 15 Accesses


  1. 1.

    By the reactions of chloral hemiacetals with dialkyl phosphorochloridites and dialkyl phosphorochloridates the corresponding phosphorous and phosphoric triesters were prepared.

  2. 2.

    The compounds obtained are biologically active.

This is a preview of subscription content, log in to check access.

Literature cited

  1. 1.

    W. T. Sumerford and F. M. Cronie, J. Am. Chem. Soc,70, 448 (1948).

  2. 2.

    West German Patent 1,049,842 (1959); Chem. Zentr.,1959, 11663.

  3. 3.

    J. F. Reinhard, M. N. Lewis, R. J. Meltzer, and J. A. King, J. Am. Pharm. Assoc., Sci. Ed.,46, 359 (1957); Chem. Zentr.,1959, 2546.

  4. 4.

    Sh. Mamedov and G. Ya. Lerner, Azerb. Khim. Zh., No. 6, 87 (1961).

  5. 5.

    K. V. Nikonorov and É. A. Gurylev, Izv. Akad. Nauk SSSR, Ser. Khim.,1967, 1872.

  6. 6.

    K. V. Nikonorov, É. A. Gurylev, and A. V. Chernova, Izv. Akad. Nauk SSSR, Ser. Khim.,1968, 587.

Download references

Author information

Additional information

Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 3, pp. 603–605, March, 1968.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Nikonorov, K.V., Gurylev, É.A., Mertsalova, F.F. et al. Relation of structure to physiological action for phosphorylated chloral hemiacetals. Russ Chem Bull 17, 582–584 (1968). https://doi.org/10.1007/BF00911615

Download citation


  • Chloral
  • Physiological Action
  • Phosphorochloridates
  • Phosphorochloridites
  • Phosphoric Triesters