The aminomethylation of 2-nitro-3-hydroxypyridine has been studied.
On aminomethylation 2-nitro-3-hydroxypyridine forms 6-monosubstituted Mannich bases.
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H. Hellmann and G. Opitz,α-Aminoalkylierung, Verlag Chemie (1960).
L. D. Smirnov, V. P. Lezina, V. F. Bystrov, and K. M. Dyumaev, Izv. AN SSSR, Ser. Khim.,1965, 198.
K. M. Dyumaev, L. D. Smirnov, and V. F. Bystrov, Izv. AN SSSR, Otd. khim. n.,1962, 883; L. D. Smirnov, S. L. Or lova, V. P. Lezina, and K. M. Dyumaev, Izv. AN SSSR, Ser. Khim.1967, 1816. 2611
Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 12, pp. 2742–2744, December, 1967.
The authors are grateful to N. M. Émanuel for his continuous interest in the work.
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Smirnov, L.D., Kartasheva, T.P., Lezina, V.P. et al. The aminomethylation of 2-nitro-3-hydroxpyridine. Russ Chem Bull 16, 2609–2611 (1967). https://doi.org/10.1007/BF00908508
- Mannich Base