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Cancerolytic peptides

Communication 9. Peptides of sarcolysine with β-alanine and with glycine

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Conclusions

  1. 1.

    New key compounds of sarcolysine viz. NPS-sare-OH and H-sarc-OBzh, and ofβ-alanine viz. H-β-Ala-OBzh have been obtained.

  2. 2.

    New dipeptides of sarcolysine withβ-alanine and glycine have been prepared.

  3. 3.

    A method has been proposed for the simultaneous removal of protecting NPS- and OBzh groups from dipeptides.

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Literature cited

  1. 1.

    A. A. B. Paulyukonis, K. I. Karpavichus, O. V. Kil'disheva, and I. L. Knunyants, Izv. Akad. Nauk SSSE, Ser. Khim., 2772 (1968).

  2. 2.

    A. A. B. Paulyukonis, K. I. Karpavichus, O. V. Kil'disheva, and I. L. Knunyants, Izv. Akad, Nauk SSSR, Ser. Khim., 133 (1969).

  3. 3.

    J. C. Sheehan and G. P. Hess, J. Amer. Chem. Soc.,77, 1067 (1955).

  4. 4.

    L. Lervas, D. Borovas, and E. Gazis, J. Amer. Chem. Soc.,85, 3660 (1963).

  5. 5.

    A. A. Aboderin, G. R. Delpierre, and J. S. Fruton, J. Amer. Chem Soc.,87, 5469 (1965).

  6. 6.

    J. Goerdeller and A. Holst, Angew. Chem.,71, 775 (1959).

  7. 7.

    B. Halpern and D. E. Nitecki, Tetrahedron Letters, 3031 (1967).

  8. 8.

    W. Kessler and B. Iselin, Helv. Chim. Acta,49, 1330 (1966).

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Additional information

This paper is published by the decision of a meeting of the principal editors of the journals of the Academy of Sciences of the USSR on July 12, 1962, as the dissertation of the work of A. A. B. Paulyukonis.

Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 6, pp. 1346–1351, June, 1969.

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Paulyukonis, A.A.B., Karpavichus, K.I. & Knunyants, I.L. Cancerolytic peptides. Russ Chem Bull 18, 1241–1245 (1969). https://doi.org/10.1007/BF00908178

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Keywords

  • Peptide
  • Glycine
  • Dipeptide
  • Simultaneous Removal
  • Sarcolysine