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Notiz zur Synthese des Nonactins

Synthesis of nonactine

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With (−)-nonactic acid and the 8-epitosylate of benzyl (+)-nonactate usingWalden inversion (−)-nonactyl-(+)-nonactic acid is constructed. The latter forms by way of its imidazolide or its α-mercaptopyridyl ester the macrotetrolide nonactine in poor yield.

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Correspondence to Prof. Dr. Ulrich Schmidt.

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Gombos, J., Haslinger, E., Nikiforov, A. et al. Notiz zur Synthese des Nonactins. Monatshefte für Chemie 106, 1043–1044 (1975).

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