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Photoreactivation of UV-damage in phage containing 5-Bromouracil-DNA


Es wird eine neue Strahlenschutzwirkung des Cysteamins gegenüber photoreaktivierbaren und nicht-photoreaktivierbaren UV-Schäden bei 5-Bromuracilsubstituierten Phagen beschrieben. BU-T1 Phagen UV-bestrahlt in Anwesenheit von 0,01 molar Cysteamin zeigen eine normale Strahlenempfindlichkeit und nahezu normale Photoreaktivierbarkeit, die bei Abwesenheit des Schutzstoffes blockiert ist. Der Mechanismus der Desensibilisierung wird diskutiert.

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Hotz, G. Photoreactivation of UV-damage in phage containing 5-Bromouracil-DNA. Zeitschrift für Vererbungslehre 95, 211–214 (1964).

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  • Cysteamin