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Enzymic and nonenzymic systems protecting photoreceptor membranes against active forms of oxygen and lipid peroxides

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Abstract

Activity of the enzyme systems protecting membrane structures of photoreceptor cells Ithe outer and inner segments of the retinal rods) against active forms of oxygen (superoxide dismutase) and lipid peroxide (glutathione peroxidase, glutathione reductase) was shown to be low. At the same time a high concentration of α-tocopherol (vitamin E) was demonstrated in these membranes. It is concluded that the polyene lipids of the retinal photoreceptors are protected against the harmful action of lipid peroxidation by the vitamin E system.

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Kagan, V.E., Lankin, V.Z., Shvedova, A.A. et al. Enzymic and nonenzymic systems protecting photoreceptor membranes against active forms of oxygen and lipid peroxides. Bull Exp Biol Med 88, 856–858 (1979). https://doi.org/10.1007/BF00869214

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Key Words

  • superoxide dismutase
  • glutathione peroxidase
  • glutathione reductase
  • α-tocopherol
  • membranes of photoreceptors