Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

The effect of total x-ray irradiation on the thalamus

  • 13 Accesses


A study was made of the functional condition of the hypothalamic area in cats following a total x-ray irradiation dose of 600 r. The functional condition of the sympathetic hypothalamic centers was measured in terms of the change in the skin potential of the sweat secreting surface of the cat's paw following electrical stimulation of the hypothalamus.

The excitability of the hypothalamic centers rose considerably after irradiation. The increased excitability was still present during the following 24 hours, and in most cases even after 3 days. Just before death, the excitability of the autonomic centers was reduced.

Analogous phasic changes of hypothalamic excitability were observed in a number of animals following their total irradiation with a dose of 50 r; these disappeared within 2 weeks after irradiation, and no radiation sickness developed.

This is a preview of subscription content, log in to check access.

Literature Cited

  1. [1]

    T. M. Efremova, Theses and Reports at the Conference on Medical Radiology, 54–55 (Moscow, 1957).

  2. [2]

    I. N. Kondrat'eva, Theses and Reports at the Conference on Medical Radiology, 43–44 (Moscow, 1957).

  3. [3]

    A. V. Lebedinskii, Med. radiol. 1, 35–41 (1957).

  4. [4]

    M. N. Livanov, Transactions of the All-Union Conference on Medical Radiology, 17–22 (Moscow, 1957).

  5. [5]

    N. P. Smirnova. Med. radiol. 3, 3–9 (1958).

  6. [6]

    A. L. Shabadash, Theses and Reports at All-Union Conference of Scientists and Engineers on the Application of Radioactive and Stable Isotopes and Radiations to Russian Agriculture and Science. 46–47 (Moscow, 1957).

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Smirnova, N.P. The effect of total x-ray irradiation on the thalamus. Bull Exp Biol Med 48, 1081–1084 (1959).

Download citation


  • Public Health
  • Irradiation Dose
  • Electrical Stimulation
  • Functional Condition
  • Phasic Change