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HLA antigens in Arab children with steroid-responsive nephrotic syndrome

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Forty-eight Arab patients with steroid-responsive childhood nephrotic syndrome were studied for the frequency of HLA-A,-B,-C and-DR antigens. HLA-DR7 was significantly increased in the patient group (63% vs. 28%,P=0.0002) confirming reports of a DR7 association in other ethnic groups and indicating a universal association with this antigen. HLA-CW6 was also significantly increased (44% vs. 21%,P corr.=0.042). HLA-DQW1 was significantly reduced in the patients (29% vs. 57%,P corr.=0.012) as was HLA-CW4 (6% vs. 24%,P corr.=0.042).

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Correspondence to Moh'd Zaki.

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Zaki, M., Daoud, A.S., Al Saleh, Q.A. et al. HLA antigens in Arab children with steroid-responsive nephrotic syndrome. Pediatr Nephrol 8, 74–75 (1994). https://doi.org/10.1007/BF00868269

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Key words

  • HLA
  • Arabs
  • Nephrotic syndrome