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Asymmetrical synthesis of organometallic analogs of natural compounds. 8. Reactions of pentafluorobenzaldehyde with the Ni(II) complex of a schiff base of glycine and (S)-2-[N-(benzylprolyl)amino]benzophenone

  • V. A. Soloshonok
  • N. Yu. Svistunova
  • V. P. Kukhar'
  • N. A. Kuz'mina
  • Yu. N. Belokon'
Organic Chemistry Methods Of Synthesis

Abstract

Reaction of pentafluorobenzaldehyde with a Ni(II) complex of a Schiff base formed from glycine and (S)-2-[N-(benzylprolyl)amino]benzophenone yields, depending on the reaction conditions, the hitherto unknown, diastereo-and enantiomerically pure amino acids 2R,3S-β-(4-methoxytetrafluorophenyl)serine, 2S,3R-β-(4-methoxytetrafluorophenyl)serine, 2S,3S-β-(pentafluorophenyl)serine, and 2S,3R-β-(pentafluorophenyl)serine.

Keywords

asymmetrical synthesis pentafluorobenzaldehyde Schiffbase fluorine-substituted β-phenylserines 

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Copyright information

© Plenum Publishing Corporation 1992

Authors and Affiliations

  • V. A. Soloshonok
  • N. Yu. Svistunova
  • V. P. Kukhar'
  • N. A. Kuz'mina
  • Yu. N. Belokon'

There are no affiliations available

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