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Multifocal peripheral neuropathy in eosinophilic fasciitis


Polyneuropathy may complicate eosinophilia associated connective tissue disease. We report a multifocal neuropathy in a patient with eosinophilic fasciitis proven by demonstrating an eosinophilic cellular infiltrate in a fascial biopsy specimen from the forearm. Sural nerve biopsy revealed lymphocytic cuffing of epineural arterioles. Although described in thel-tryptophan-related eosinophilia-myalgia syndrome, peripheral neuropathy with these features has not been previously noted in a patient with eosinophilic fasciitis who had not consumedl-tryptophan.

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Correspondence to Michael Donaghy.

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Satsangi, J., Donaghy, M. Multifocal peripheral neuropathy in eosinophilic fasciitis. J Neurol 239, 91–92 (1992). https://doi.org/10.1007/BF00862980

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Key words

  • Eosinophilic fasciitis
  • Multifocal polyneuropathy