Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

De novo hemolytic uremic syndrome following renal transplantation

  • 30 Accesses

  • 3 Citations

Abstract

We report a case of complete recovery of renal function in a patient with de novo hemolytic uremic syndrome (HUS) following renal transplantation. This 3-year-old girl had none of the factors known to contribute to the development of HUS in transplant recipients. This case illustrates the usefulness of renal biopsy in the accurate diagnosis and management of dysfunction in the allograft following renal transplantation.

This is a preview of subscription content, log in to check access.

References

  1. 1.

    Gasser VC, Gautier E, Steck A, Siebenmann RE, Oechslin R (1955) Hämolytische-Urämische Syndrome: bilaterale Nierenrindennekrosen bei akuten erworbenen hämolytischen Anämien. Schweiz Med Wochenschr 85:905–909

  2. 2.

    Campos A, Sibley R, Kim Y, Miller K, Michael AF (1981) The hemolytic uremic syndrome. Kidney 14:23–30

  3. 3.

    Drummond KN (1985) Hemolytic uremic syndrome then and now. N Engl J Med 312:116–118

  4. 4.

    Habib R, Levy M, Gagnadoux MF, Broyer M (1982) Prognosis of the hemolytic uremic syndrome in children. In: Hamburger J, Crosnier J, Grunfeld JP, Maxwell MH (eds.) Advances in nephrology, vol 11. Year Book Medical, Chicago, pp 99–128

  5. 5.

    Hebert D, Sibley RK, Mauer SM (1986) Recurrence of hemolytic uremic syndrome in renal transplant recipients. Kidney Int 30:S51-S58

  6. 6.

    Van-Buren D, Van-Buren CT, Flechner SM, Maddox AM, Verani R, Kahan BD (1985) De novo hemolytic uremic syndrome in renal transplant recipients immunosuppressed with cyclosporine. Surgery 98:54–62

  7. 7.

    Pillay VKG, Kurtzman NA, Manaligod JR, Jonasson O (1973) Selective thrombocytopenia due to localised microangiopathy of renal allografts. Lancet II:988–991

  8. 8.

    Magalhaes RL, Braun WE, Straffon RA, Hoffman GC, Shainoff JR, Osborne G, Deodhar SD (1975) Microangiopathic hemolytic anemia in renal allotransplantation: report of a successfully treated case and review of the literature. Am J Med 58:862–868

  9. 9.

    Hutton MM, Prentice CRM, Allison MEM, Duguid WP, Kennedy AC, Struthers NW, McNicol GP (1970) Renal homotransplant rejection associated with microangiopathic haemolytic anemia. Br Med J 3:87–88

  10. 10.

    Lichtman MA, Hoyer LW, Sears DA (1968) Erythrocyte deformation and hemolytic anemia coincident with the microvascular disease of rejecting renal homotransplants. Am J Med Sci 256:239–246

  11. 11.

    Petersen VP, Olsen TS (1971) Late renal transplant failure due to the hemolytic-uremic syndrome Acta Med Scand 189:377–380

Download references

Author information

Correspondence to Blanche M. Chavers.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Chavers, B.M., Wells, T.G., Burke, B.A. et al. De novo hemolytic uremic syndrome following renal transplantation. Pediatr Nephrol 4, 62–64 (1990). https://doi.org/10.1007/BF00858442

Download citation

Key words

  • Hemolytic uremic syndrome
  • Renal transplantation