Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Synthesis of lysine-containing oligopeptides using ortho-nitrophenylsulfenyl protection

  • 26 Accesses

Conclusions

Employing the acid chloride, carbodiimide, and azide methods, and using carbobenzoxy and o-nitro-phenylsulfenyl protection, we obtained the heptahydrochloride of the methyl ester of Gly-L-Lys6-Gly.

This is a preview of subscription content, log in to check access.

Literature cited

  1. 1.

    D. E. Olins, A. L. Olins, and P. H. von Hippel, J. Mol. Biol.,33, 265 (1968).

  2. 2.

    J. C. Sheehan and G. P. Hess, J. Am. Chem. Soc.,77, 1067 (1955).

  3. 3.

    L. Zervas, D. Borovas, and E. Garis, J. Am. Chem. Soc.,85, 3660 (1963).

  4. 4.

    V. V. Bondar, V. A. Shibnev, and K. T. Poroshin, Dokl. Akad. Nauk Tadzh. SSR,13, No. 5, 14 (1970).

  5. 5.

    M. Brenner and W. Huber, Helv, Chim. Acta,36, 1114 (1953).

  6. 6.

    K. Schwyzer and H. Kappeler, Helv. Chim. Acta,44, 1991 (1961).

  7. 7.

    R. Neher, J. Chromatogr.,1, 122, 205 (1958).

  8. 8.

    A. Neuberger and F. Sanger, Biochem. J.,37, 515 (1943).

  9. 9.

    V. A. Shibnev, T. D. Kozarenko, and K. T. Poroshin, Izv. Akad. Nauk SSSR, Otd. Khim. Nauk, 1500 (1960).

  10. 10.

    B. F. Erlanger, H. Sachs, and E. Brand, J. Am. Chem. Soc.,76, 1806 (1954).

Download references

Author information

Additional information

Deceased.

Translated from Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, No. 10, pp. 2305–2308, October, 1972.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Poroshin, K.T., Bondar, V.V. & Shibnev, V.A. Synthesis of lysine-containing oligopeptides using ortho-nitrophenylsulfenyl protection. Russ Chem Bull 21, 2236–2238 (1972). https://doi.org/10.1007/BF00855305

Download citation

Keywords

  • Methyl
  • Chloride
  • Ester
  • Methyl Ester
  • Azide