Springer Nature is making Coronavirus research free. View research | View latest news | Sign up for updates

Conversion of β-alanine in vivo and in isolated liver tissue

  • 15 Accesses

  • 1 Citations

Summary

β-alanine was incubated with chopped liver tissue of rats in oxygen for 160 minutes at 37°C. It was established that a certain part of added β-alanine (about 12%) disappears, causing an excessive production of urea and of a small quantity of β-alanine.

In parenteral administration of β-alanine an increased urinary excretion of this amino acid is observed in B6-deficient rats in which the process of β-alanine transformation is disturbed.

This is a preview of subscription content, log in to check access.

Literature Cited

  1. [1]

    A. E. Braunshtein and R. M. Azarkh, Biokhimiia 22, 430–437 (1957). See English translation.

  2. [2]

    A. E. Braunshtein and E. V. Goriachenkova, Biokhimiia 2, 163–179 (1949).

  3. [3]

    V. V. Grechko, Biokhimiia 22, 2, 736–743 (1957). See English translation.

  4. [4]

    N. P. Meshkova and S. E. Severin, Practical Manual of Biochemistry of Animals, Moscow (1950). In Russian.

  5. [5]

    A. N. Parshin, T. A. Goriukhina and E. A. Gromyko, Problems of Medical Chemistry v. 1, 217–226, Moscow (1949). In Russian.

  6. [6]

    L. G. Razina, Doklady Akad. Nauk SSSR 111, 1, 161–164 (1956).

  7. [7]

    S. E. Severin and U. Wei Min, Doklady Akad. Nauk SSSR 120, 364–367, 1314–1317 (1958). See English translation.

  8. [8]

    P. Fusier, Bull. Soc. Chim. Biol. v. 32, 180–186 (1950).

  9. [9]

    K. V. Giri, A. N. Radhakrishnan and C. S. Vaidyanathan, J. Indian Inst. Sc. v. 35, 145 (1953).

  10. [10]

    S. Grisolia and D. P. Wallach, Biochim. et biophys. acta v. 18, 449 (1950).

  11. [11]

    J. Graff and H. D. Hoberman, J. Biol. Chem. v. 186, 369–372 (1950).

  12. [12]

    H. Levine and A. H. Smith, J. Lab. a. Clinic. Med. v. 11, 168–172 (1925).

  13. [13]

    A. Pihl and P. Fritzson, J. Biol. Chem. v. 215, 345 (1955).

  14. [14]

    E. Roberts and H. Bregeff, T. Biol. Chem. v. 201, 393–398 (1953).

  15. [15]

    T. Winnik, R. E. Winnik, Biochim. et biophys. acta v. 23, 649–650 (1957).

Download references

Author information

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Severin, S.E., Wei-Min, U. Conversion of β-alanine in vivo and in isolated liver tissue. Bull Exp Biol Med 46, 1335–1338 (1958). https://doi.org/10.1007/BF00845176

Download citation

Keywords

  • Oxygen
  • Public Health
  • Urea
  • Liver Tissue
  • Urinary Excretion