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Folinic acid responsive seizures: a new syndrome?

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  1. Hyland K and Bottiglieri T (1992) Measurement of total plasma and cerebrospinal fluid homocysteine by fluorescence following high performance liquid chromatography and precolumn derivatization witho-phthaldialdehyde.J Chromatogr 579: 55–62.

  2. Hyland K and Clayton PT (1992) Aromaticl-amino acid decarboxylase deficiency: diagnostic methodology.Clin Chem 38: 2405–2410.

  3. Joseph MH, Davis P (1983) Electrochemical activity ofo-phthalaldehyde-mercaptoethanol derivatives of amino acids. Application to high-performance liquid chromatographic determination of amino acids in plasma and other biological materials.J Chromatogr 277: 125–136.

  4. Matson WR, Langlais P, Vollcere L, Gamache PH, Bird E, Mark KA (1984)n-Electrode three dimensional liquid chromatography with electrochemical detection for determination of neurotransmitters.Clin Chem 30: 1477–1488.

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Correspondence to K. Hyland.

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Hyland, K., Buist, N.R.M., Powell, B.R. et al. Folinic acid responsive seizures: a new syndrome?. J Inherit Metab Dis 18, 177–181 (1995).

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  • Public Health
  • Internal Medicine
  • Folinic Acid
  • Responsive Seizure
  • Folinic Acid Responsive Seizure