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Wound-healing phenomena around percutaneous devices implanted in rabbits

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The major factor determining percutaneous implant success is the formation of a stable skin-implant junction. The objective of this study was to gain more insight into the mechanisms underlying implant-skin reactions. For this purpose, plasma-sprayed, dense hydroxyapatite and titanium implants were inserted into the tibia and on the cranium of 15 rabbits. The implants were leftin situ for 9 months. Clinical and histological investigations were performed. It was found that especially direct attachment to bony skeletal tissues favours the longevity of percutaneous implants. No differences in soft tissue reaction between the various implant materials was observed.

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Jansen, J.A., Van Der Waerden, J.P.C.M. & De Groot, K. Wound-healing phenomena around percutaneous devices implanted in rabbits. J Mater Sci: Mater Med 1, 192–197 (1990).

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  • Polymer
  • Titanium
  • Soft Tissue
  • Hydroxyapatite
  • Factor Determine