A series of compounds (DAP-AA) composed of an amino acid (AA) and a dialkyl phosphoryl group (DAP) is the basic elements of life chemistry. Self-catalysis of DAP-AA gives the self-assembly oligopeptides, even in aqueous medium at 38°C. The oligo-nucleotides could also be assembled from nucleosides' phosphorylation by DAP-AA. DAP-AA acts as the energy source as well as the phosphoryl donor for the synthesis of nuclic Acids and protein. A general expression for the self assembly system is proposed.
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Zhao, Y., Cao, P. Phosphoryl amino acids: Common origin for nucleic acids and protein. J Biol Phys 20, 283–287 (1995). https://doi.org/10.1007/BF00700446
- basic element of life chemistry
- model expression
- phosphoryl amino acids
- Origin of life