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An unusual organelle in a case of duchenne muscular dystrophy

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Summary

A new organelle found in a case of Duchenne muscular dystrophy is described. It was located at the periphery of a regenerated myofibre close to a satellite cell. It was roughly sperical in shape and 0.30–0.35 μm in diameter. Its internal structure was examined in serial and tilted sections, and consisted of parallel arrays of laminae or, possibly, filaments. The nature of the organelle is briefly discussed.

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References

  1. Cullen MJ, Watkins SC (1981) The role of satellite cells in regeneration in diseased muscle. In: Marschal G, Guba F, Takao O (eds) Mechanisms of muscle adaptation to functional requirements. Pergamon Press, Oxford and Academiai Kiado, Budapest (in press)

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Additional information

Supported by grants from the Muscular Dystrophy Group of Great Britain and the Medical Research Council

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Watkins, S.C., Cullen, M.J. An unusual organelle in a case of duchenne muscular dystrophy. Acta Neuropathol 54, 329–330 (1981). https://doi.org/10.1007/BF00697009

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Key words

  • Muscular dystrophy, Duchenne type
  • Ultrastructure
  • Satellite cell