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Reaction of sterically hindered 1-hydroxy-3-imidazoline 3-oxides with phenyllithium

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The reaction of 3-imidazoline 3-oxide derivatives with phenyllithium followed by oxidation affords nitroxyl radicals of the 2-imidazoline or 2-imidazoline 3-oxide series depending on the nature of the substituent in position 2 of the heterocycle.

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Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 2, pp. 292–294, February, 1994.

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Reznikov, V.A., Volodarsky, L.B. Reaction of sterically hindered 1-hydroxy-3-imidazoline 3-oxides with phenyllithium. Russ Chem Bull 43, 272–274 (1994). https://doi.org/10.1007/BF00695827

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Key words

  • imidazoline
  • nitroxyl radical
  • nitrone