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Synthesis of 3-fluoroalkyl-2-aziridinyl ketones

Abstract

Simple and efficient methods for the synthesis oftrans-3-fluoroalkyl-2-aziridinyl ketones from polyfluorinated α,β-enones have been developed.

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Additional information

For the previous communication, see Ref. 8.

Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 2, pp. 282–284, February, 1994.

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Khomutov, O.G., Filyakova, V.I. & Pashkevich, K.I. Synthesis of 3-fluoroalkyl-2-aziridinyl ketones. Russ Chem Bull 43, 261–263 (1994). https://doi.org/10.1007/BF00695824

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Keywords

  • trans-3-fluoroalkyl-2-aziridinyl ketones
  • β-aminoketones
  • α-bromo-α,β-enones
  • α,β-dibromoketones