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Crystalloid inclusions reminiscent of Hirano bodies in autolyzed peripheral nerve of normal Wistar rats

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In a study of experimental autolysis of peripheral nerves of normal Wistar rats, crystalloid inclusions similar to Hirano bodies were observed. They occurred in the nuclei and cytoplasms of Schwann cells and in myelinated axons. They first developed after a 12-h autolysis and increased in number and size with time. Their fine structure, localization, and morphogenesis are discussed in relation to the autolysis of the cellular organelles.

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Correspondence to S. Yagishita.

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Yagishita, S., Itoh, Y., Nakano, T. et al. Crystalloid inclusions reminiscent of Hirano bodies in autolyzed peripheral nerve of normal Wistar rats. Acta Neuropathol 47, 231–236 (1979). https://doi.org/10.1007/BF00690551

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Key words

  • Hirano bodies
  • Peripheral nerve
  • Autolysis
  • Wistar rat