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Hydroxyurea-induced acute alveolitis in a Patient with chronic myeloid leukaemia

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Summary

A number of cytotoxic agents have been implicated in the production of widespread pulmonary alveolar damage. We present a case of life-threatening alveolitis in a patient on hydroxyurea for chronic myeloid leukaemia. The clinical course suggests that the alveolitis was induced by the hydroxyurea. This is the first reported case of hydroxyurea-induced pulmonary alveolitis.

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References

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    Gibson GJ (1987) Drug induced lung disease. In: Weatherall DJ, Ledingham JGG, Warrell DA (eds) Oxford textbook of medicine. Oxford University Press, Oxford, pp 15141–15144

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    Rosenow EC III (1980) Chemotherapeutic drug-induced pulmonary disease. Semin Respir Med 2 (2): 88–96

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Author information

Correspondence to Graham H. Jackson.

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Jackson, G.H., Wallis, J., Ledingham, J. et al. Hydroxyurea-induced acute alveolitis in a Patient with chronic myeloid leukaemia. Cancer Chemother. Pharmacol. 27, 168–169 (1990). https://doi.org/10.1007/BF00689105

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Keywords

  • Cancer Research
  • Myeloid Leukaemia
  • Chronic Myeloid Leukaemia
  • Cytotoxic Agent
  • Hydroxyurea