Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Hydroxyurea-induced acute alveolitis in a Patient with chronic myeloid leukaemia

  • 34 Accesses

  • 18 Citations


A number of cytotoxic agents have been implicated in the production of widespread pulmonary alveolar damage. We present a case of life-threatening alveolitis in a patient on hydroxyurea for chronic myeloid leukaemia. The clinical course suggests that the alveolitis was induced by the hydroxyurea. This is the first reported case of hydroxyurea-induced pulmonary alveolitis.

This is a preview of subscription content, log in to check access.


  1. 1.

    Gibson GJ (1987) Drug induced lung disease. In: Weatherall DJ, Ledingham JGG, Warrell DA (eds) Oxford textbook of medicine. Oxford University Press, Oxford, pp 15141–15144

  2. 2.

    Rosenow EC III (1980) Chemotherapeutic drug-induced pulmonary disease. Semin Respir Med 2 (2): 88–96

Download references

Author information

Correspondence to Graham H. Jackson.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Jackson, G.H., Wallis, J., Ledingham, J. et al. Hydroxyurea-induced acute alveolitis in a Patient with chronic myeloid leukaemia. Cancer Chemother. Pharmacol. 27, 168–169 (1990).

Download citation


  • Cancer Research
  • Myeloid Leukaemia
  • Chronic Myeloid Leukaemia
  • Cytotoxic Agent
  • Hydroxyurea