A number of cytotoxic agents have been implicated in the production of widespread pulmonary alveolar damage. We present a case of life-threatening alveolitis in a patient on hydroxyurea for chronic myeloid leukaemia. The clinical course suggests that the alveolitis was induced by the hydroxyurea. This is the first reported case of hydroxyurea-induced pulmonary alveolitis.
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Jackson, G.H., Wallis, J., Ledingham, J. et al. Hydroxyurea-induced acute alveolitis in a Patient with chronic myeloid leukaemia. Cancer Chemother. Pharmacol. 27, 168–169 (1990). https://doi.org/10.1007/BF00689105
- Cancer Research
- Myeloid Leukaemia
- Chronic Myeloid Leukaemia
- Cytotoxic Agent