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Damage of skeletal muscle in rats by immunoglobulins

II. Ultrastructural studies

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An experimental model of the autoimmune process was developed to study the ultrastructural aspects of immunomyopathies. Every type of muscle fibre organelle was affected and the severity of injury increased in direct proportion to time following immunization. It is suggested that ultrastructural methods are useful in studies concerned with the analysis of structural aspects of experimental immunomyopathies.

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Korényi-Both, A. Damage of skeletal muscle in rats by immunoglobulins. Acta Neuropathol 34, 207–218 (1976). https://doi.org/10.1007/BF00688676

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Key words

  • Immunomyopathy
  • Muscle disease
  • Electron microscopy
  • Experimental muscle pathology