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Computer editing of morphometric data on nerve fibers. An improved computer program

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A short guide is given for the planning of nerve fiber morphometry using computer-assisted methods. A new computer program is introduced which allows, among other factors, correction for myelin sheath shrinkage. If myelin shrinkage is not corrected for, there will be false high values for axon caliber and false low values for sheath thickness. The magnitude of the skew produced by this factor is shown on hand from computer editing.

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Dedicated to Prof. F. Seitelberger on the occasion of his seventieth birthday

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Friede, R.L. Computer editing of morphometric data on nerve fibers. An improved computer program. Acta Neuropathol 72, 74–81 (1986).

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Key words

  • Nerve fiber morphometry
  • Computer program
  • Myelin sheath thickness
  • Tissue preparation