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Synthesis of 2-alkylthioquinazol-4-ones

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Alkylation of 2-thioxoquinazol-4-one by different alkylating agents was studied, and it was found that the reaction proceeds at the exocyclic sulfur atom with the formation of 2-alkylthioquinazol-4-ones.

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Literature cited

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    Kh. M. Shakhidoyatov, S. Yu. Yangibaev, L. M. Yun, and Ch. Sh. Kadyrov, Khim. Geterotsikl. Soedinin, No. 1, 112 (1982).

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 2, pp. 254–256, February, 1987.

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Yun, L.M., Yangibaev, S., Shakhidoyatov, K.M. et al. Synthesis of 2-alkylthioquinazol-4-ones. Chem Heterocycl Compd 23, 214–216 (1987).

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  • Sulfur
  • Organic Chemistry
  • Alkylation
  • Sulfur Atom
  • Alkylating Agent